Just wondering, Red_34 & Lori, did you go right on the full dose of Colazal, 3 capsules at a time? I started at 1 capsule per dose, then increased to 2 per dose for another couple days, then went up to 3 per dose. That was the way my 1980s gastro had me start on new 5ASAs: start low & gradually increase to see how the body adjusts.
The Colazal gave me an exceptionally dry mouth at 1st, but I kept drinking water thoughout the day & otherwise did better with it than on any other oral 5ASA. But I cannot tolerate it at full-dose for longer than 9-10 weeks w/o developing side effects such as puffy eyelids. Good luck, Lori, I hope it helps you. / Old Hat (nearly 30 yrs with left-sided UC; currently on 3 Colazal daily for maintenance of remission)