That's great news, Annie!!!!!! Colazal was my break-through med & many other members writing here have similarly good results with it-- so glad to hear it makes improvement for you, too. It apparently dissolves farther along in the colon than earlier 5-ASAs & therefore seems to do a good job relieving left-sided inflammation. Best wishes for steady progress toward remission! / Old Hat (nearly 30 yrs with left-sided UC; currently on 3 Colazal daily for maintenance of remission)