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too much Salofalk?

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Posted 2/26/2010 8:25 PM (GMT 0)
I keep reading that the max of mesalamine is 4.8g a day..my doc prefers me on 6g a day and was not happy when i decided to take 9 instead of 12 pills a day.

Is this drug harmful to the kidneys or any other part of the body in tehse large doses?

 

Posted 2/26/2010 9:20 PM (GMT 0)
I think he's just being stubborn in not prescribing you the enemas.

My doc wants me on a lower dosage oral 5ASA and higher rectal.

So..makes sense to put the money and dosage where the issue needs to be addressed.

I personally would refuse the higher dosage of Salofalk oral and push for the enemas. You've read more than enough info and have enough input from others who use the both ends approach to say you need the enemas.

quincy
Posted 2/26/2010 9:41 PM (GMT 0)
I think it is harmful to some if you take too much for too long. You can look online for reviews of Asacol and similar drugs and find more information. I, personally, am more worried about being in a flare than taking a higher dose of 5asas right now but when in remission, you shouldn't take that high of a dose over a long period of time. A recommended maintenence dose is usually 2400mg a day orally, some people take a bit more, like 3600mg, some even take 4200mg but 6000mg for long term is a high dose although I am sure plenty of people take it and are fine.

I agree with Quincy, you can take the medication rectally with no harmful effects, it is topical. I find it strange when doctors don't want to prescribe enemas. I am thankful my doctor is the opposite, she is all about rectal meds.

here are some reviews for Asacol

http://www.askapatient.com/viewrating.asp?drug=19651&name=ASACOL

Posted 2/27/2010 7:18 AM (GMT 0)
Even weirder is that my doc started me on them 21 years ago...not like it's a new idea.

Krissy...maybe you can say you want to try them anyway.

q
Posted 2/27/2010 10:31 PM (GMT 0)
Yeah, I firmly believe that GI's should also recommend rectal applications. I'm about to see my GI on Thurs and I will ask him to re-prescribe me some. I intend to give them another go. Quincy promotes their use at every opportunity to the extent of it almost being her raison d'etre. I'm sure she does this from sound personal experience.

However the problem I see (speaking from my own earlier fleeting experience), is that one's rectum/anus is in such a fragile/tender/heavily inflamed condition at the time of inserting a suppository, or the even more intrusive liquid enemas which are very difficult to 'retain', especially when an inflamed colon's natural reaction is to summarily discharge anything and everything in the rectum.

I suspect there are some tried and true 'tricks' to effectively overcome these application difficulties, and that some kind person can enlighten me.

The use of corks maybe? wink
Posted 2/27/2010 11:38 PM (GMT 0)
I think if one's anus is in a huge problem state, the ointments are a good option to use in conjunction with the inserted liquids, suppositories, etc.
Proctocedyl is one I've used with success....the bottom line is to try and deal with issues as quickly as possible.

For me, external hemmies and fissures can be problematic, and with just a few bms where I tend to push...that will exacerbate them even more. Even worse, it seems that if I don't deal with them, a flare is soon behind...don't realise a
connection unless it's just inflammation in general in such close quarters.

Medications can be used in conjunction with one another or if rectal meds are used at night, then maybe an ointment mediction that can be used externally or just into the anus is a good option.

Corks wouldn't work....again, one would have to insert it..and it's much bigger and porous and rougher than a suppository (eyeballs a poppin). Of course wittled down might be an option..lol!

I don't know if the enemas are a reason for my existence...(yes, had to look it up), but they're a good help in one's quality of life!

quincy
Posted 2/28/2010 2:15 AM (GMT 0)
I'll certainly ask him about proctocedyl. I suspect it's a soothing/anasthetic ointment? Ok, I'll look it up...
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