Posted 4/28/2010 6:13 PM (GMT 0)
My understanding of pred use during pregnancy is that there is a very, very slight increased risk of cleft palate if it's used in the first trimester. I think that the risk of that would be much lower if you're using proctofoam. Honestly, if I were flaring badly, and not getting better with other meds, I'd for sure use proctofoam in the first tri, and would strongly consider pred.