My doctor told me I need to be on birth control because of the drugs she started me on. Has anyone had issues with the pill while taking Prednisone or Prograf? Most UC patients haven't heard of Prograf because it is only used in extreme cases from what I've heard. But most UC patients know Prednisone....so any advice here? I have heard there is always a possibility of my UC meds decreasing the pill's effectiveness.