Remicade-Prednisone combo and now the blood is back

After my first Remicade infusion the blood disappeared literally overnight. Now less than a week later the blood has returned along with less formed stool. My second infusion is not scheduled until June 4th. My GI is not concerned and said that most people see affects after the 2nd infusion. I am continuing to taper on prednisone at this time. I am at 8mg but my GI said that I can go back up to 10mg to control symptoms if I want too.

My question: Should I tough it out at 8mg of Prednisone and take Tylenol 3s for pain (headaches, bodyaches from pred taper) or should I go back up to 10mg to control the symptoms and have less BMs and no blood? My GI has left the decision up to me.

I am having such a hard time getting off of the pred that I am concerned if I go back up to 10mg it will take me even longer to get off of this stuff. How do people taper off of pred when starting Remicade? How long did it take and what were your side effects?

I am continuing with Cortifoam in the AM and Mesalamine Enemas at night. Trying to keep in good spirits but I am a little discouraged today.

As much as I hate Prednisone, I would go back up to 10. Inflammation leads to more inflammation. If you can get it under control by spending a little more time at 10, it would be worth it.

Don't lose hope! You've only just begun the Remicade! They call the first 3 infusions a "loading dose" for a reason.

I think it's hard to gague how your symptoms are but if you're feeling miserable, go up to 10mg. I hope you're able to get off prednisone completely in a few weeks after your next infusion. Many people don't respond to Remicade right away, it takes time. Try to stay positive.