Hi,
I am looking for feedbackback on methatrexate. I have had mild UC for over 15 years, with increase in symptoms in the last few years. I have been fortunate enough to never have been hospitalized or have surgery, but experienced my first bad flare a few months ago. I have been on the max dose of Asacol for the last 10 years, and when that along with Rowasa did not help, I was put on prednasone taper, which worked really well until the prednasone was done. I was put on a smaller dose taper with same results and am now on 3rd taper, and Rheum. prescribed Methatrexate as well, for extra-intestinal symptoms of inflammation & joint issues. I have been struggling with adhesive capsulitis for the last year (frozen shoulder caused by inflammation - very painful), and this is also a manifestation of my inflammatory process. I am very concerned and fearful of the Methatrexate, as I know there are very serious side effects, I feel sick, hair fallling out (but that was happening before),and have to get blood work done & no alcohol, tylenol, etc. I have found that I am having worse swelling after only 3 weeks, and am wondering if this is the disease process accelerating, or if it is caused by Rx. Any thoughts or feedback is appreciated.