Starting LDN tonight

Jim,

So glad you'll be able to start LDN.

I think you're doing it the right way - 4.5mg.

Yes, the time to take it is between 10pm and 2am.

As far as what to expect:

1) some sleep problems - this typically lasts about 2 weeks until your body adjusts. And the way to get around that is to take L-Threonine amino acid powder at night (my suggestion is 20 min before or after the LDN).

2) vivid dreams - some have them, some don't. It is not a tell-tale sign of it working vs. not working.

3) you may come down with some sort of flu initially, as your immune system gets ramped up. I got a 24 hour type flu with sore throat, body aches, chills, etc.... which lasted a little more than 24 hours and then disappeared entirely (I did nothing but let the symptoms move through and out).

4) Absorption issues - unfortunately there's no magic sign for this. If you are having malabsorption issues (as I had them), then the LDN just won't work and you won't have any effects positive or negative, and will have to switch to transdermal LDN.

5) If you are already on an SCD type diet (and I know you are), wherein you've taken gluten and dairy out of your diet, you should see some results pretty quickly - from within a few days to a few weeks. Those who aren't on restricted GFDF diets, generally may take much longer to see any results, from weeks to months.

I hope it helps you, and I wish you good luck.

Please do keep us apprised of your weekly progress.

 

Jim,

Ok, I understand now.

After speaking with Skip's, it seems that some people have vivid dreams and some don't, and apparently that is NOT an indication of whether it is being absorbed or not.

I really don't remember if when I first started avicel filler LDN,  did it give me vivid dreams??However, I can tell you that when I was in between LDN formulations, and tried the liquid LDN, which DID NOT WORK, I did NOT have any vivid dreams, and then when I went back onto absorbable (for me and my gut) type of LDN in sublingual troche, I had vivid dreams again.

Skip's told me that many people don't have vivid dreams, and if they do it's only initially, and then it wears off. But they told me that in my case since I had a history of effective LDN + vivid dreams, and non-effective LDN + no vivid dreams, that it probably did translate to absorption=vivid dreaming.

I hope I've answered your question.

I hope to hear more and better results within the next few days from you.

 

Jim,

 It's looking like back to back single motion days...for the first time over 6 months. ANd that's only after 3 nights on LDN.

That is good. Before I started LDN, I was bleeding at a 10 (0 to 10, with 10 being the WORST), and after my 3rd day the bleeding was at a 3 or 4, then at day 7 it was at ZERO!

So, yes you can get good results rather quickly (especially if you are on gluten, dairy, wheat free diet).

Keep us apprised of your progress.

heh, it's not working quite as well for me. I have pancolitis...maybe I need 8mg for it to start working. lol

Jim,

Did you have the severe cramping before the LDN also?

I had severe headaches and cramping with the avicel filler, that's the reason I am asking.

Somedude,

LDN does not work that way: more is better.

Are you taking it at the right time, ie. between 10pm and 2am?

Are you combining the LDN with dairy,wheat,gluten free diet?

Sounds like you are doing the right thing then Somedude. Give it time brutha!

InSo - no I didn't have the cramps prior. they're not as abad today so hopefully they will ease completely. It is listed as a transitory side-effect so hopefully it will all be fine by the second week. Remembering i didn't ramp up my doasge...i just went straight in at 4.5mg

cramps have eased a bit but i'm still not 'firming up' and still ahve some urgency. I guess it's early days so must stay positive. definite improvement in frequency however.

Jim, yes I see it's not all roses yet...
But I am very concerned about your cramping - that is usually a sign IMO of intolerance to the filler.

If it continues, I would suggest you call or email Skip's to get their advice,no?

By the way InSo, when yuo first started on LDN with Avicel fillers what reaction did you get? Cramping also?

Thanks InSo, that's really interesting.

It has been a particularly rough morning today. I only just made it to a work toilet on the way in from the carpark at 8:15 and that was #3 for the day :( Have had cramping again and some nausea and loss of appetite. I can't afford to lose much more weight either.

Anyway I rang the pharmacy again today and they're making up a transdermal batch for me at 4.5mg in 1g of cream. The pharamcist was very helpful and was also a GAPS practitioner. But they havent had many UCers on LDN at all (mainly MS suffereres) so they're fairly inexperienced when it comes to to LDN & UC. Anyway it will take about 5 days before I get the cream and it's not that much more expensive. In the meantime they have suggested lowering the does by splitting the cap in half and taking either 1/3 or 1/2 dose until I get the cream. I will try that but if that doesn't work I may just stop until I get the TD cream.

How does that sound to you?

I have also booked into see a new gastro specialist who has a good rep in NZ. I haven't got a specialist yet so it will be interesting to see him. Not sure what to expect tho.

Thanks for Skip's email I will contact him.

She advocates no filler as her preference is for Transdermal cream rather than pills. And I'm going to try that.

With regard to pill fillers She has mentioned Sucrose being superior to AVicel (Microcrystalline Cellulose) for LDN.

The pills i'm currently taking have filler which is equivalent of Avicel I believe. And that's the one she has had cramping problems with also.

I just had high hopes and it's so darn frustrating when that doesn't pan out. It's also frustarting when you can't quite pin down the cause of reactions when trying out new things. You see I did actually have a stomach cramp along with my flu/cold last week before I even started LDN...so who knows it may actually be something else entirely but I think it's the LDN as teh cramps are far more frequent & sustained tahn the one off cramp I had prior to starting LDN.

Jimbo NZ said...
She advocates no filler as her preference is for Transdermal cream rather than pills. And I'm going to try that.

With regard to pill fillers She has mentioned Sucrose being superior to AVicel (Microcrystalline Cellulose) for LDN.

The pills i'm currently taking have filler which is equivalent of Avicel I believe. And that's the one she has had cramping problems with also.

I just had high hopes and it's so darn frustrating when that doesn't pan out. It's also frustarting when you can't quite pin down the cause of reactions when trying out new things. You see I did actually have a stomach cramp along with my flu/cold last week before I even started LDN...so who knows it may actually be something else entirely but I think it's the LDN as teh cramps are far more frequent & sustained tahn the one off cramp I had prior to starting LDN.

I believe and this is my opinion, that your cramping is not caused by the filler. I could be wrong, but I stand by that.