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Adenosine: An immune modulator of inflammatory bowel diseases

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Posted 1/16/2013 6:11 PM (GMT 0)
I have been researching more at the cellular level and found this. I dont think it has been discussed here yet. I will need help understanding it more and of course more research. It seems caffein effects it in the cells.

Adenosine according to wikopedia..

http://en.wikipedia.org/?title=Adenosine

Adenosine: An immune modulator of inflammatory bowel diseases

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751993/

adenosine and IL12

http://lib.bioinfo.pl/pmid:11023991

Caffein and adenosine...I would be curious to know how caffein daily effects any of you here. I personally avoid it and have always.

Adenosine and caffein..

http://www.ncbi.nlm.nih.gov/pubmed/20164566

Once again I am not even sure where I am going with this but thought it was intertesting and will keep poking around on it.

Adenosine receptor agonists for promotion of dermal wound healing

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671632/

one more thing...

Methotrexate's anti-inflammatory effect may be due to its stimulation of adenosine release.

OM what do you think? Perhaps a way to promote the adenosine in our bodies. I think thats next for me to look into. Appreciate anyone wanting to kick this around a bit. Looks like there is tons of info on it relating to IBD and wound healing etc...I need to learn more.

Yet more. I searched on how to increase it in our bodies..

They show a 3 step process at Livestrong..

http://www.livestrong.com/article/400918-how-to-boost-atp-levels/

Steve

Post Edited (twiggs) : 1/16/2013 11:59:12 AM (GMT-7)

Posted 1/17/2013 5:09 PM (GMT 0)
Well it seems that if we take care of our mytochondria which produce all forms of Adenosine or ATP we would ensure adequate amounts of this. It all goes back to our Mytochondria strangely enough which are the power houses of every cell in our bodies.

Feed your mytochondria and not your taste buds it seems to always go back to this. To be healthy we have to understand what our cells and most importantly what our mytochondria need. I am reading that mytochondria gone awry are being suspected in some serious diseases like parkinsons and altheimers and others. It reminds me of the video of the doctor who cured herself of stage 2 MS by eating for your mytochondria. If anyone wants the link to the video I can provide it if your interested.

Steve
Posted 1/17/2013 5:36 PM (GMT 0)
Looks like Melatonin protects our mytochondria. I also see that melatonin is found in cherries. I think melatonin is important for all of us. I personally would get it naturally in foods than a supplement and in moderation of course.

For those wondering what this all means as far as UC goes. I beleive that our problems stem from cellular disfunction possibly due to nutritional difficiencies and or destructive diets / lifestyles.


http://en.wikipedia.org/wiki/Melatonin

Post Edited (twiggs) : 1/17/2013 10:42:39 AM (GMT-7)

Posted 1/17/2013 6:19 PM (GMT 0)
If you ever needed a reason to drink more beer, I found it..see above for more on Melatonin.

http://www.ncbi.nlm.nih.gov/pubmed/19249143

cheers!
Posted 1/17/2013 8:22 PM (GMT 0)
Twiggs: Good find,one way to increase is to not eat antagonists. Coffee,tea,chocolate,I even found quercetin to be an antagonists of the receptors.  Years ago if I ate lots of chocolate UC would get worse. Today not so much.

Old Mike

 

Posted 1/18/2013 1:31 PM (GMT 0)
OM, Great news on the other things that act as antagonists. I think any tea with caffein with the exception for herbal teas which have no caffein would be ok. I didnt know about quercetin though which is very interesting. I would love to comprise a list of antagonists and just avoid them completely.

Steve
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