Posted 1/28/2013 9:21 AM (GMT 0)
Hey, I was wondering if any one has any information if 6-mercaptopurine (Purinethol) has any negative impact on bodybuilding/muscle growth?
I tried to google but didn't seem to find anything.
How ever this is all I could really find involving the words 'muscle' 'protein synthesis' etc I don't have much idea if this has anything to do with my question though.
"6-MP ribonucleotide inhibits purine nucleotide synthesis and metabolism. This alters the synthesis and function of RNA and DNA. Mercaptopurine interferes with nucleotide interconversion and glycoprotein synthesis."
http://en.wikipedia.org/wiki/Mercaptopurine
And..
"http://www.ncbi.nlm.nih.gov/pubmed/3787651
Thanks.