Differential immunomodulatory properties of Bifidobacterium logum strains: relevance to probiotic se

This is actually interesting. Many, many years ago Elaine Gottschall author of Breaking the Viscous Cycle said the almost very same thing as this study in a response to a question asked in a forum. This must have been some 10 plus years ago...

What she said exactly was she felt that Bifo can go either way (good or bad) depending on what's going on in the colon. Therefore she said stay away form it till the gut has a chance to heal first as a precaution till she has had some time to read through and fully digest what is going on to try and understand it. Also she mentioned looking this up in the library at the University and finding study after stud after study on this stuff. She commented that she was surprised there was so much information... She wondered what in the world or why people keep doing the same studies over and over... The information is there.. just that no one is looking she said...

Really struck a cord with me 8 years ago. (Also 8-10 yeras ago they though maybe 200 species... not 10,000 as is now)

I searched for that post but have not found it yet - but in this response (See below) posted to the same question, she gives is very similar - just further ahead in the future answer. It's worth a read...

Regardless is you follow SCD or not... I will say Elaine was wise beyond all others in many ways... She was a remarkable person - can't quite find the right words...

-----------
Bifidus

Elaine writes:
Bifidis is normally the only gut bacteria present in breast fed babies. Early researchers felt that when bifidis persists into early childhood and beyond, it correlated with celiac disease. I, personally, do not believe in using bifidis in a probiotic or in a yoghurt culture.

The use of different strains of probiotics has been a subject of much discussion. I do not pretend to know the answers for most of them and have told the list that spending one year doing library research convinced me that there is more ambiguity than black and white answers.

To further the confusion, very smart people are advising some very dumb things. Companies have jumped on the band wagon proposing oral administration of various types of Lactobacillus strains along with things like bifidis and have given absolutely no attention to the fact that these bacteria will mutate depending upon what is in the colon for them "to eat."

Seth on healing crow referenced a wonderful article which was a chapter in a book written by his former professor of bacteriology at the University of Wisconsin. (copyright 2000 Kenneth Todar. Bacteriology pg 303. I have it in front of me.

"The normal flora of humans is exceedingly complex and consists of more than 200 species of bacteria. The makeup of the normal flora depends upon various factors including genetics, age, sex, stress, nutrition and diet of the individual......The distribution of the bacterial flora of humans is shown in the following table. This table lists only a fraction of the total bacterial species that occur as normal flora of humans and does not express the total number or concentration of bacteria at any site."

It then goes on to list many species including Bacteroides sp and Bifidobacterium bifidum. I understand that these two are closely related. Others include Enterobacteriaceae (E. coli) and Lactobacillus, etc.

Then comes the confusing part:
" The greatest number of bacteria are found in the lower intestinal tract, specifically the colon and the most prevalent bacteria are the Bacteroides, a group of Gram-negative, anaerobic, non-sporeforming bacteria. They have been implicated in the initiation of colitis and colon cancer. Bifidobacterium bifidum is the Gram-positive counterpart to the Bacteroides in the colon. They are anaerobic, non-sporeforming, lactic acid bacteria. They are the "friendly" bacteria in the intestine. Bacteroides predominate in the intestine of meat-eaters, bifidobacteria and other lactic acid bacteria predominate in the intestine of vegetarians."

From Elaine:
That said, it appears that bifidis could replace bacteroides and the implication of the latter in initiating cancer and colitis could be overcome. However, that is not certain and considering that our paleolithic diet was high in meat, I would doubt if meat is the real suspicious element in the diet. The research has indicated to me that any work done to support this thesis was not done without many other variables in the diet including high starch. Seth provides the following information:

"Intestinal Floras of Populations That Have a High Risk of Colon Cancer

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Sept. 1995, p. 3202-3207 Vol. 61, No. 9

The study finds that populations with the highest colon cancer risk have a higher number of bifido bacteria than populations with the lowest risk. The authors were very surprised at this result since bifido bacteria is a "good" bacteria. Of course this is an epidemiology study (which always have flaws) but combined with Elaine's knowledge on the subject sends a powerful warning in my mind.

t writes:
In the case of bifidus, it has a tendency to overgrow. Each type of bacteria has different properties, different byproducts... I usually think of it in terms of different levels of tenacity and agression. Your gut is truly a multicultural society - some member are more altuistic, and others are criminal. Some are interested in improving the neighbourhood, and some are only out for themselves.

L. Acidophilus is about as community-minded a bacterial strain as you will find, with S.Thermophilus and L.Bulgaricus running a close second. The others are either less friendly, or are unknown quantities. It gets even more complicated if you consider soil based strains.

So we stick with Acidophilus in our supplements, and Acidophilus, Thermophilus and Bulgaricus in our yoghurt, because they are good neighbours.

Julie writes:
I am one who had used yoghurt containing Bifidus as my starter the first eight months on the diet and after a few back to back flares where nothing helped, Lucy clued me in that the Bifidus may have overgrown in my colon and therefore caused my endless flare. Sure enough, after I switched to the powdered yogourmet starter I literally came out of the flare overnight! I am a big proponent

From the LI listserve

Hi Mike, very cool. I should have guessed that you spoke with her seeing how you have been trying so many things over the last while of me being on this forum. You must find it interesting in some ways to see how things have progressed over time. Would be unreal to hear her thoughts on things now. She used to live not that far away from me along with some early SCD folks so it was always easy to talk and get advise etc. Even though it wasn't the cure or long term remission I had hoped. Anyway that a whole other topic.

I recall reading your stuff on NO and on Olive Oil... Oddly, I came across this last night: Suggesting that you add Asprin to your daily EVOO... I'd be very curious to see the results if any as long as it's safe and all that fun stuff.

http://www.sciencedaily.com/releases/2013/02/130221141250.htm