Posted 3/7/2013 4:49 PM (GMT 0)
I am not sure why you'd want to break the dosage up like that, take one in the morning and one at night. You'd end up with the same exact amount of medication in your body within a 24/hour period so I would guess the result would be the same whether you took it all at once, or split the dosage up. Do you think you need a stronger dosage of mercaptopurine or something if so ask your GI?
I take my mercaptopurine in the late evening as I am getting ready for bed. I do this as I heard it might cause nausea for some and I didn't want to risk it. I am at 50mg, so I have only the one caplet to take.