Are mesalamines not working for me?

How do you know if mesalamines aren't working? I was on 4 Lialda a day for 2 weeks - switched to Colazal 9 a day because the Lialda was making me sick to my stomach - and have been on that for 2 weeks. So 4 weeks total.

For the last 3 weeks I've been on Rowasa and Canasa nightly. I also did a 4 week prednisone taper and stopped at 2.5 mg on Monday.

I seem to get better in the beginning and then I seem to plateau. Going 1 to 4 times in the morning. Some D some formed some harder pieces. Some days tiny bit of blood, some days none, some days more.

Are the mesalamines just not going to get me where I need to be?

I have been taking Asacol for over 2 years. I know it helps me but it has never gotten me to "where I need to be". I can't quit taking it because I know it helps me. Sometimes having UC is like trying to find the end of a rainbow. You see it right over that hill and then when you get there, whammo, it's over the next hill. Sometimes I wonder if there really is a pot of gold.

I don't know. I tried fiber way back 10 years ago and had such a horrible reaction that I didn't go back to it until 6 months ago. I'm using the metamucil psyllium capsules and I'm happy with my 1/2 serving per day (3 capsules).