Full pills in stool

There was a topic about this yesterday, I think the person said their stool was too acidic.

the coating dissolves at ph 7 or greater, which is basic - not acidic. you need to reduce acid in your GI trac.

It starts to break down in the terminal ileum and throughout the colon.

Part of the reason could be fast transit...are you taking it with food or not?

You also have c.diff...maybe that's in part the problem or the vanco?

So, were you not always on Asacol? or did you just start taking it?

q

I really bet it's the C. diff, Chrissy. Don't blame it on your diet! The C. diff definitely makes your transit time faster, so there's MUCH less time for the coating to dissolve. Also, the C. diff might screw with your gut pH.

It's not too strange, given that Asacol is coated to NOT dissolve until it hits your colon. There aren't a whole lot of meds that are made that way, so most of them would be dissolved before they get to your colon. Because you have C. diff, stuff is probably moving through your colon at warp speed, and therefore the Asacol doesn't have time to dissolve.

This is not uncommon with Asacol. There have been many mentions of this in here. And for this was certainly the case when I was on Asacol. I would see them in there from time to time and they were probably many more times I did not see them because they were covered.
I never got close enough a look though to be able to tell if what I was seeing was a completely undigested pill or just the shell of the pill. Others have speculated the same, don't know if you got that close a look.
Incidentally, I have never seen a Lialda pill in my BM.

you could just grind off some of the coating to force it to open sooner. or check into Pentasa, which is not coated. or slow down your transit with lots of Imodium. or it is possible a higher protein diet might raise pH. I think some prorobiotics facilitate pH-raising fermentation - but I am not sure.

But do not obsess about food, or say things like these pills would dissolve except that "I eat too unhealthy". In past threads it has become pretty clear you obsess over food. Avoid whatever highly processes high-salt high-sugar foods you can, but otherwise you and diet should not even be in the same room without help from a therapist. It is too much of an issue for you, with too many distorted notions.

Check out Pentasa.

For some readignon Asacol and pH, seeL gut.bmj.com/content/48/4/571.full

Yeah, I've never known if mesalamine works for me in general because I've always been on something else too. But, never seen pills in my stool before. So not sure if it is working or not in general. I used to use lialda when I was first diagnosed and loved it but then again I was on Pred too.

really?, when my gi suspected c.diff he sent me to lab to give stool sample, but told me to take anti-diarrhea meds in meanwhile. how does the danger manifest?

I took Imodium 3 times without realizing that, do I need to do something or just ride it out?

I did so what do I do?

I'd do fibre supplements to help sweep it out.
Definitely do NOT do Imodium again...

q