There are two schools of thought on using nicotine for the treatment of UC. One is that it is the nicotine that helps with UC as some studies show that nicotine patches help (
www.ncbi.nlm.nih.gov/pmc/articles/PMC2014383/).
I have heard others state that it is something in the smoke along with the nicotine that help UC although I have not been able to find much scientific data on that assumption.
The article in the above link mentioned that 70% of people given a nicotine liquid enema had improvement. I would love to try a nicotine enema if they ever come out. I wonder if you could make your own?