Pathogenkiller question regarding Benadryl

I want to make clear there are different types of histamines. Taking benydryl might help out with certain kinds of histamines and possibly UC but it will not do anything for dietary histamines. I actually don't follow a low histamine diet as I take the digestive enzyme DAO, ordered from Swanson, which helps eliminate excess dietary histamines. Please google a low histamine diet as I don't think you are correct in eliminating red meats. You would have to eliminate certain meats, but not red meats in general. Usually anything processed or anything aged has high histamines such as certain meats, cheeses, and fruits. The riper the fruit, the higher the histamine count. Most alcohols are high in histamines. Yeasts of all kinds are high in histamines. As I said in the other thread if you are having a problem with histamine intolerance you should see almost immediate improvement, say in about one week. If you don't see any improvement in one week going on a low histamine diet then quit. It is not like other diets where people will tell you that you have to do it religiously for weeks, months, or years before you see improvement. A low histamine diet I don't classify as a lifestyle change, it is just changing your diet away from foods that are hurting your UC due to a histamine intolerance. If you are not histamine intolerant then you don't need this change.

Prob try dao like Gary suggested, maybe Benadryl at night for a few days. I think that any relief would be masking real issues ( likely something methyl cycle related) but you can try. To me histamine reactions are a sign of much bigger issues.

This might be of some assistance to you:

"In August I wrote about our experience with histamine and depression, but in the last couple of months I have figured out that I didn't have it quite right. I thought that he was having problems because of low copper, and his copper probably was contributing a little, but now I really have the answers.

Over two years ago my son started having problems after having had antibiotics. I realize now that his gut dysbiosis made it so that he doesn't absorb proteins very well. He became deficient in methionine, the amino acid precursor to SAMe, which is used to donate a methyl group to histamine in order to degrade the histamine. He also has a few mutations in his methylation cycle that probably have contributed to his problems, but the main problem is that, even though GAPS is a diet high in methionine, his methionine levels are not high enough to make enough SAMe to get rid of the histamine. A year ago I had him tested for the MTHFR gene mutations and he was positive for the MTHFR 677 gene and we started him on methylfolate and he felt better within a couple hours of having a 5 mg dose. However, although he was feeling better, it just was draining more homocysteine from his supply and he was in a downward spiral. I have also had him tested by 23andme recently and he has CBS C699T +/- and A360A +/+ which were probably draining his homocysteine levels at a higher rate, too, so after a few months he started feeling worse and worse, and I kept finding ways to deal with the symptoms, like taking lots of vitamin C. I started giving him methyl B12 about a week ago and it was like magic. He felt so great! But after 2 or 3 hours he would have to take more and after a couple days of this it wasn't working any more. I realize now that this is because MTR, which uses methylfolate to change homocysteine into methionine, has feedback inhibition from low homocysteine and he was making less and less methionine synthase and slowing down his methylation cycle to a crawl.

Now he is feeling fine after taking enough methionine to replenish his supply of homocysteine. Eventually we hope that GAPS will heal his gut enough so that he will be able to absorb all the nutrients he needs, but he isn't there yet. But at least now he isn't getting any die off symptoms, when he used to get symptoms just from eating any food. "