How much money you think is needed for next step to or maybe even cure for UC.

Maybe just my ilogical thinking. I am in great remision but I think if just 10 percent of people with UC will donate money to search for cure or to be closer few steps to the cure why dont we do that.

Lets say it this way there are some number of people with Uc and if just 10 or 20 percent will donate money to organisation that only research cure and that organisation will hire few great labs to search for cure. Lets say it 200 usd per month from 20 percent of people with UC.

I really believe and this is important that we will have cure sooner Really sooner.

I also believe that there is a lot of people that are willing to give money for that some more some less depending on their circumstances.

I know this sound a bit crazy but you have health insurance companies. But if you will have organisation that is only researching UC we will have huge breaktrough with that amount of money and for lots of people in the world UC is there greatest problem.

Imagine paying money for resolving just your greatest illness not anything else.
I am not for stopping paying health inssurance just if we had a lot of money for researching just this disease it will be great.

After all will you be willing to pay for it.

Please answer the question and can you say me your opinion.

Funny play is just something I have had in my mind when I was registering.
There is majority of people on this forum with the same problem. there are probably 0,0001 percent in the world with uc. If just 10 percent of people give some money for cure.....
Maybe I am romantic

Are you kidding? They've probably donated over a billion dollars overall to Muscular Dystrophy and they still don't have a cure for that. Might as well throw your money away donating to a political candidate so they can use their position to make millions for themselves. Sorry, but I'm not on board with this one. I have to save my money to buy expensive prescriptions.

Lets say it this way. People with Uc dont have unity ( I am really sorry about thta bont ban me ) to solve their problem

Just one thing.
Money is everthing in this world if we have enough money we will have a maybe nit a cure but we will be one step more to the cure

It's not just an issue of throwing money at the problem to fix it. Look at how much funding breast cancer research, for example, gets? Have they cured it yet? Nope. Yet a few less common cancers are easily treated and put people in long remissions pretty easily.

With UC research, there are more problems than just not enough funding. IBD research actually gets about 100 million in grants from the US government every year. http://report.nih.gov/categorical_spending.aspx

That's not even going into how much money is being spent in other countries to research this disease.

The problem with most diseases aside from infectious disease and organ failure is that we do not yet have great tools to reliably understand and make sense of their complexity. Technology is advancing, but as of yet, it is very difficult to analyze large amounts of genetic data in a way that makes more sense. Most of our understanding of IBD comes from mouse models of the disease, and they only really study how inflammation arises when the mucus barrier goes away. That ignores many other possible factors involved in someone getting UC, so if all we have to go by are possibly inaccurate models, we have deeper problems in research than just not having enough money to cure UC, and these are just a few of the obstacles.

But not all is bad, these mouse models are useful for studying the process of inflammation, and have given us better insight into how we might be attacking our own gut bacteria. There are a bunch of new drugs in the pipeline, including an oral drug for Crohn's that stops inflammation really well and we will likely see use in UC too. The 12 week remission rate is 67% in phase II trials, which is much better than most of the drugs we have to take. While it's too early to get excited, these results are very hopeful. : https://www.healingwell.com/community/default.aspx?f=17&m=3217673

Aside from that, scientists are starting to successfully grow working human intestines. Holy cow, if we ever got to a point where scientists can study human colons from us directly, that will advance research so quickly, I get excited just thinking about it.

If you want to really help find a cure, don't just throw money at it. Support your country's government funded research organization (like the NIH in the US), vote for politicians that would likely be pro-research and pro-science, and most importantly, volunteer for any basic research studies in your area whenever they pop up.

Post Edited (Tunnelvisionary) : 10/23/2014 5:28:05 PM (GMT-6)

I hate to be a partypooper, but lets get our heads straight. If we talk of the 'cure', it will NOT comes from the US for absolutely any disease. If you look closely how the US medical system works, it would cripple the profits of the corporates (individuals according to the US legal system) dedicated to that disease/disorders.

I will put more money on countries like Canada, Sweden, Finland, Singapore and all with nationally run healthcare system to find the breakthrough.


@Marauder93,
Yes it is, but one who has never worked in the lab or shopped for any equipment, its hard for them to visualize the cost. When I told my Dad (he has extensive lab experience) that I bought a PCR comb from Bio-Rad for ~$100, he asked me if the comb is made of Platinum !! 50c Plastic stuff is sold for ~$100, talk about expenses.

"I don't think even 10% of the people on this board signed up for the completely free genetic research project at 23andme. Out of 1 million IBD sufferers in the USA only 2500 signed up so far. 7500 empty spots left"

don't remember seeing this, but I'm sure I just missed it - thanks -

"Fact is that many that have the disease are terrified of effective treatment or a cure. UC has become their life and identity. "

hmmm, I think you're wrong -


" I don't know why people are like that or why so many people are apathetic in general these days. You can't even get people to vote anymore."

unfortunately, you are absolutely right !

Who knows,there might even be a cure out there already,but ignored,missed,forgotten by the gi community.

We are also missing lots of medical data on the net say from about 1930-1970ish.

There are also many clinical trials,that seem to complete,yet no published results,what's with that.

Here is just one example, seemingly ignored/forgotten,dont know if an actual cure but seems to induce a nice

remission. Might depend on the definition of cure.

If we define cure as a sustained remission without meds for the rest of your life,might be difficult.

http://www.ncbi.nlm.nih.gov/pubmed/8358131
http://www.ncbi.nlm.nih.gov/pubmed/17551835

here is one of my threads on protease inhibitors-inexpensive

https://www.healingwell.com/community/default.aspx?f=38&m=2966352

FMT might be a cure and we don't know it yet,once they get it refined it might work much better.

Poop pill. Not real expensive.

MAP vaccine might be a cure for Crohn's,will have to wait and see on that,possible one time shot.-inexpensive

Another ignored one is histamine blockade, with mast cell stabilization-inexpensive.

I am sure that there are many others I have not mentioned here.

Old Mike

 

To put this in more practical terms, a lot of people who have UC are unemployed or underemployed due to the illness. Others struggle with the burden of paying for expensive medications, treatment and surgeries. $200 a month is a lot of money to many people. As another poster pointed out, a $1 million budget takes you almost nowhere in research.

Research grows exponentially when mulit-million dollar grants from foundations start flowing in. Despite how it may seem when you come here, UC just isn't that common an illness. Money flows usually to the issues that affect the most people and in the most severe ways. A disease that will kill you draws more donations than one that usually "only" makes your life miserable.

I strongly disagree with anyone who keeps on suggesting that there will never be a cure because the pharmacutecial companies can only make profits by selling us maintenance meds and don't even try to find cures for things. That is really prejudiced thinking and I have the proof. Look at the newer Hepatitis C drugs that ARE cures. Of course they cost about $100,000 but that's my point. There's big money in cures, they don't have to keep us sick to make money. If someone came up with a cure for IBD they wouldn't have any trouble at all making billions of dollars selling the cure. The fact is that most diseases are just so complicated that they haven't been able to figure out how to make a cure, but they would if they could, and the Hepatitis C drugs are the smoking gun.

Good points and, on top of that, these drug companies (many of them small pharma) are corporations with shareholders and stock value. Anytime a drug does good in a trial the stock for that company goes waaaay up and conversely, if a drug trial fails, the stock value for the company can plummet. Many of these companies live on the fringe. If they don't make a good drug or have even one failure they can go out of business. If they find a cure, the company stock appreciation turns them into instant billionaires. I also agree that it is the researchers who will find the cure because you can't ever find a cure for anything unless you figure out what is wrong in the first place and they are the ones who will do this, not the drug companies. The drug companies actually have the easy part.