Combination therapy using fexofenadine ( antihistamine) for chronically active ulcerative colitis

www.ncbi.nlm.nih.gov/pubmed/16944185

This report suggests that histamine and mast cell activity may be important pathophysiological factors responsible for persistent clinical and mucosal inflammatory activity in ulcerative colitis despite the use of steroids.

Clinical disease activity and established serological markers were recorded during 6 weeks of unsuccessful therapy and during the next 6 weeks, as a new nonsedative antihistaminergic drug, a mast cell stabilizer, and an hypoallergenic diet were implemented in addition to conventional therapy. Induction of remission was achieved within 2 weeks after treatment with fexofenadine, disodium cromoglycate, and an amino acid-based formula. Clinical disease activity, stool frequency, leukocytes, c-reactive protein, and orosomucoid levels in serum decreased rapidly. Daily steroid administration could be gradually reduced along with 6 weeks of this treatment.

Another point for antihistamines. I am curious about the diet as well. Perhaps I will give Allegra another try. I took it when I was pregnant and it didn't really help me much with my allergies.

Thanks for sharing.

Kefir is also a potent mast cell stabilizer, though people have to beware of dairy intolerance. More here (studies always provided :) ).

Best.

Wallaby strawberry kefir is the best tasting drink I have ever had period - unfortuantely depsite all those probiotics I cannot tolerate it.

So if we improve on Benadryl it is a sign to go further and try fexofenadine or Zyrtec in combination ?

Investigating OM's thread on the topic..