Sounded like Nitrates are only good if you have the mouth bacteria to convert them to nitrites ?
I had a dentist once tell me I had the least amount of saliva he had ever seen.
Mike & Mark said...
Mark; I have a old big thread on excessive nitrates.
But now have to start wondering if something wrong with our oral bacteria in the conversion to nitrite.
It might even make some sense that IBD starts in the mouth and the dysbiosis or whatever works its way down,since the mouth
gets the first assault from anything we put into our body. How this might cause UC to start in the rectum, hard even to guess.
Low nitrate/nitrite/NO in circulation might lead to poor circulation in the rectum,or less bacteria killing.
Interesting that the conversion to NO from arginine is a longer pathway, where from nitrate quite easy do to mouth bacteria.
The trick might be that inos is not so good,but NO from dietary nitrite/nitrate down regulates inos and increases mucus thickness.
So the success that some have by eating spinach even though it contains arginine is the nitrate/nitrite in the spinach,
spinach contains some of both, but the nitrate will be converted to nitrite by oral bacteria, if the right ones are still alive.
Old Mike
Never have done any genetic testing.
Chewing might help,not sure. Once nitrate gets into your blood then it can get into the saliva.
But chewing spinach may help to get the nitrate to the oral bacteria faster.
As you can see by eating high nitrate food the alternate NO pathway can take over from the enzyme inos path,to some
extent.