Salofalk Suppositories after one use all of sudden made me worse?

okay so ive been in and out of flaring for the past 2 years with proctitis, maximum time i was "flare free" a month and even then i continually have mucous.
So ive been using these suppositories since forever it seems like. At the start of january i got out of a flare. due to steroid enemas and vitamin e enemas. i was med free for a few weeks and decided to try a suppository over night to see how i would handle it. The next morning i had bad stomach pain, a huge blob of clear orangey brown substance came out follow by TONNES of mucous clear mucous but tonnes. This was a huge step back from just ONE night of a suppository. So i didnt do it again and i went back to my norm of having some mcuous no blood but just some mucous. Clearly the suppository weirdly made me worse. My concern is in the past few months its almost like all of a sudden my body rejects these? sooooooo what on earth am i supposed to do for a medication that is a maintenance med? Im scared to try a enema version of this since what if this also makes me worse? has anyone experienced this??? will the enemas be different- but my thoguhts are if its the same emdication what could be different. I dont want to take a step back but at the same time i need a maintenance med i think other than vitamin e?