Ordered Second Ubiome Kit Today

Gary what steps you took would you attribute as the biggest factors in getting you to 99% remission?

Is taking DAO supplement safe in long run?

DAO is totally safe long term and you can't even overdose on it, even if you take the whole bottle all at once.

My first sample was with a different company. It isn't like 23andme, where you have to get it translated. They just list what you have and how much. One category had a graph chart which showed I had 98% Firmicutes and about zero Bacteriodetes when those ratios should have been more like 45% to 45%. After researching the internet I found Grape Seed Extrract lowers Firmicutes and raises Bacteriodetes so I gave it a whirl and it seems to have worked. The report lists everything in your sample and how much you have of all of them.

Like Gary, my sample came back saying that I was very high in firmicutes and low in bacteriodes. I saw that he had started grapeseed extract for that problem and, after researching the safety of grapeseed extract, I decided to try it too.

Within a few days, my very soft stool (sludge) became significantly more formed. That was with just one capsule a day. Most days I try to take two capsules but I often forget and take just one. Either way, I definitely see a difference.

Note to anyone considering grape seed extract: I have to take it with food or it makes me very nauseous.

Gary, I also did American Gut the first time and am soon going to send a sample to UBiome. I'll post the results.

It will be really interesting to hear what your results are this time.

I think about your initial results from time to time because of the large proportion of staph in your first test. It's pretty crazy actually. But I struggle to think of something even remotely logical.

1) I think about sampling - I don't know how the sample is collected, but if you're not taking a bunch of poop and mixing it up and then sampling from there, your only really getting a very small snapshot. So let's say you swab the toilet paper or just the outside of your poop then you're just getting that particular spot. Which could maybe lead to the strange initial results. That being said, I could be way off as I've never bothered to read the methods for fecal sampling in some of the transplant studies. Maybe before you do this one, take some time and read through the methods they use and duplicate it somehow as best you can from home. If your really feeling brave, perhaps collect, then slice your poop in half and swab across the entire diameter to give a better representation of total population diversity.

2) Have you ever looked into cell wall deficient staff infection? (Edit: I should add that it fits in the "kinda out there" type thing)... however some bacteria eg. Staph Aureus and Step bacteria etc have been suggested to revet to cell wall deficient forms in the presence of antibiotics etc... as a defence mechanism. Actually there is a bit of a hypothesis that suggests increased antibiotic use (antibiotics that target cell wall synthesis) have put pressure on bacteria to revert to cell wall deficient forms which are causing problems in some of us with certain HLA types.

I mention this simply because of a recent conversation with that pathologist who is noticing what he feels are cell wall deficient bacteria in some blood samples given to him. Though that is Crohn's, there have been suggestions of these (intracellular) in UC from time to time.

I actually popped into the pathology lab at the hospital in person yesterday as they have preserved biopsy samples from my first, untreated colonoscopy. I am going to get them to slice the samples and put them on glass slides. I'll send them to the pathologist and he is going to test them for any DNA from MAP, Strep, Staph etc etc. Because the samples are washed before they are preserved and mounted on a slide, the only thing that should show up will be intracellular or strongly adherent bacteria.

Other than those two things I cannot really think of why your results were so darn imbalanced...

In any case the results of your progress are intriguing. Exciting.

Post Edited (Canada Mark) : 8/5/2015 9:23:01 PM (GMT-6)

All very interesting. I have looked into my staph thing somewhat but not to the extent that Mark has. Since I believe my UC was brought on by antibiotics this all makes sense to me. I always kind of questioned my first results because it took them several months to analyze them from the time I took the sample. Who knows to what extent different things grew during that time period although they claimed they accounted for that. Maybe thats why the staph was at such a high rate.

Huh - thats a good point to.. diet change just prior.

In any case, what's more far important is you're feeling exponentially better. That's all thats really matters over the how's and why's.

We've had a lot of people post results in the past and, overall, the results were all over the place, including several that seemed to match the results of normal people. I think the researchers would have already figured something out if there were a particular species that was common to all. I think it has more to do with a particular individual's immune response to a particular species in them and that it is probably different in just about everyone. It is my personal opinion that, in most cases, a particular person has species "X" in their guts and a triggering event happens, turning that person's own immune system against that species "X" when it hadn't been before. The cure would be to tell the immune system to go back to the way it was and not target species "X" anymore. Everyone's species "X" is probably a different species.

Having said that, my particular gut microbiome was waaaaaaaaaaaay off and since theoretically getting it back into balance, I have been doing incredibly better. I had some kind of staph bacteria in my gut that was 313 times the normal level. I'm very interested in seeing how my next results match up to my first results.

One thing I found very interesting from my round one results was that I had been on probiotics VSL#3 and Prescript Assist for several months before sending in my sample and the results didn't show even one strain from either one of those two probiotics, despite the fact that both probiotics are very helpful to me. You've got to also remember that these results only show what comes out of you and maybe not certain species that stay in and do not come out (if this is actually possible). Some probiotics actually die off but are still useful even in their inert form and I don't know if these would show up in the analysis or not.

Make sure it is Grape Seed Extract, not Grapefruit Seed Extract. I buy Olympian Labs 400 mg capsules. Started off with one capsule per day but did much better taking two capsules per day. Taking three made me worse initially but then later tried three again and it didn't do that but didn't seem to help that much either so I went back down to two per day again.

Hope it works. Fingers crossed. Let us know.

Just an FYI every one. What you think you are getting may in fact be something else entirely:


www.nutraingredients-usa.com/Research/Study-finds-widespread-adulteration-of-grape-seed-extract

Any idea how to reduce unclassified bacteria?