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UC and colon/rectal cancer

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Ulcerative Colitis
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Posted 1/11/2016 2:28 PM (GMT 0)
Does UC truly increase risk for these cancers?

Has anyone here gone from UC into colon cancer?

Thanks- Jay
Posted 1/11/2016 2:53 PM (GMT 0)
long time no see - welcome back !

good question - my belief is just like with uc - it's takes a multitude of factors - and being the lucky recipient of uc, may be the final chink to send you down C road -

why do you ask ?
Posted 1/11/2016 3:01 PM (GMT 0)
Thanks for the reply

Just trying to stay healthy-

I always have bit of pesky bleeding, especially if I skip the canasa for more than a couple of days.

The ONLY good thing I can say about UC is that it has forced me to clean up my diet -- eliminate sugar and junky carbs, which has in turn caused me to feel physically better overall.

I was just thinking that people with UC have a lot more attention paid to their colons vs. general public who may ignore colon care/health.
Posted 1/11/2016 4:10 PM (GMT 0)
The odds of Colorectal cancer are higher for uc patients than the general population. about 5 percent of uc patients will get CRC. That increased risk applies to only patients with pancolitis or proctosigmoiditis who've been diagnosed for 10 or more years. Patients with uc limited to their rectum (ulcerative proctitis) have no increased risk, remains the same as the general population. Luckily, increased screening through colonoscopy usually picks up dysplasia (pre-cancerous cells) prior to it becoming CRC. Even if you were to get CRC, you'd be a happy j-pouch patient. Uc doesn't increase our odds of death, CRC is very slow moving/progressing and usually caught early.
Posted 1/11/2016 5:31 PM (GMT 0)
How often are your scopes?

Stats are not subjective....they're for whom they have reviewed.

If you are bleeding because of inflammation, you need to either up the canasa to twice daily, start enemas 4g, try steroid supps in conjunction with canasa or a combo with the enemas etc.

Get the doc to take a look-see and go from there.

Are you on probiotics?
Are you on fibre supplements?
Are you on oral 5ASA?
q
Posted 1/11/2016 5:50 PM (GMT 0)
I up the canasa to twice daily if I start bleeding -- usually will start bleeding a bit if I forget canasa for 3+ days.

If that happens and I hit the canasa twice a day for a week or so, I am covered. I would be much better off if I didn't get feeling good and ignore it taking it.

My UC is really low down, so I have never gotten relief from oral meds, and I have tried several. I get good results from canasa or 4g emenas, so I have always been happy to stick with them.

I take psyllium seed powder 2x/day, stay off from sugar and junky carbs; also take turmeric and Vitamin D. Probiotics I get from fermented foods; supplements goof me up- and that's after trying just about everything out there.

Scope every 2 years or so - full colon scope and flex/sig. colonoscopy every 5 years and flex/sigs a few times in between.
Thanks- Jay

Post Edited (JayGuitar) : 1/11/2016 10:53:04 AM (GMT-7)

Posted 1/11/2016 6:11 PM (GMT 0)
Reconsider the oral....low dosage like apriso maintenence dosage. The reason is to help keep sigmoid and above treated. It's believed to have a protective quality regarding cellular changes towards cancer.

Its dedinitely easy ro skip and forget meds when we're doing well.

q
Posted 1/11/2016 7:23 PM (GMT 0)
Thanks!

I will bring that up with my GI the next time we meet -
Jay
Posted 1/11/2016 7:30 PM (GMT 0)
Please do, because this is a life-long thing. Salicylates have always been a positive in the colon cancer prevention category (if one isn't sensitive to them).

I had some scopes earlier after diagnosis that had some microscopic minute inflammation above the sigmoid. Nadda since then....so I'll attribute some of it on the consistent dosage of oral 5ASA.
Just because your UC is limited, it's not a full guarantee that it won't spread upward...it's a somewhat slower process I would think.

Just a bit of help, anyway.
q
Posted 1/11/2016 7:34 PM (GMT 0)
I will definitely inquire about it-
Should be at the GI doc in a month or so-

Jay
Posted 1/11/2016 7:39 PM (GMT 0)
There is an increased risk but that number is in decline because of better therapies and better surveillance.
Many patients have dysplasia and remove their colons that might likely become cancerous
Posted 1/11/2016 9:07 PM (GMT 0)
i've read many articles in medical papers which state exactly that according to the latest research there is absolutely no evidence that uc increases chances for developing cancer. It would be too time consuming for me to translate them but the main points supporting this idea were the following:
- uc is an indefinite disease assuming so many manifestations that it is impossible to draw any statistically significant conclusions
- globally there aren't enough uc cases to be juxtaposed against the healthy population so again we can't get any conclusive results
- the majority of "healthy" population develop cancer all of a sudden and without any prior chronic inflammation. In contrast, many patients with the most extreme cases of uc can persevere for years, have surgery and never develop cancer
Posted 1/12/2016 1:31 AM (GMT 0)
I've lived with UC of the sigmoid colon and rectum for 29 years and have yet to have any cancer. Colonoscopy back in July found two polyps, one in the rectum and one in the right side of my colon, one was a neoplasm, both benign. Not the first time I've had a benign neoplasm in a colonoscopy. I have them done every two years. The sigmoid part of my colon showed some mild activity where my colitis is concerned in my colonoscopy. Hope things continue that way. Even having UC that long, your chances are still low, mine has stayed in remission pretty well. I haven't had a flare that I would recognize by usual symptoms in who knows how long.

Post Edited (at wit's end) : 1/12/2016 9:39:25 AM (GMT-7)

Posted 1/12/2016 3:40 AM (GMT 0)

ewafromwarsaw said...
i've read many articles in medical papers which state exactly that according to the latest research there is absolutely no evidence that uc increases chances for developing cancer. It would be too time consuming for me to translate them but the main points supporting this idea were the following:
- uc is an indefinite disease assuming so many manifestations that it is impossible to draw any statistically significant conclusions
- globally there aren't enough uc cases to be juxtaposed against the healthy population so again we can't get any conclusive results
- the majority of "healthy" population develop cancer all of a sudden and without any prior chronic inflammation. In contrast, many patients with the most extreme cases of uc can persevere for years, have surgery and never develop cancer


i think i'll go with this one -
Posted 1/16/2016 1:43 AM (GMT 0)
Sounds good to me also.
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