Low crp and ESR levels

Tick41

Regular Member

Joined : Feb 2016

Posts : 331

Posted 6/11/2016 2:06 PM (GMT 0)

I am in what seems to be a flare. Constantly having to go with loose stools. Had bloodwork done this week and my ESR is low as well as my CRP both well in the normal range. Anyone else have low markers even when they are flaring?

DBwithUC

Veteran Member

Joined : Feb 2011

Posts : 4545

Posted 6/11/2016 3:17 PM (GMT 0)

those markers often fail.

but if there are motility issues instead of inflammation issues, you would expect low. could be ibs-d secondary to ibd

iPoop

Forum Moderator

Joined : Aug 2012

Posts : 16483

Posted 6/11/2016 4:46 PM (GMT 0)

There are some false positives and false negative results with crp. Accuracy of crp is about 91 percent in this one study. Source: www.ncbi.nlm.nih.gov/pubmed/7497838

You might have a small amount of inflammation causing you trouble.

Ss800

Regular Member

Joined : Feb 2016

Posts : 69

Posted 6/12/2016 3:39 AM (GMT 0)

I'd ask for a fecal count test. My crp is always low but my ESR does go up. It could be a false negative or it could be IBS. I dealt with a lot of symptoms that mimicked a flare and it ended up being IBS.

Tick41

Regular Member

Joined : Feb 2016

Posts : 331

Posted 6/12/2016 1:28 PM (GMT 0)

Seems to definitely be a flare just because I've been taking steroid enemas for about a week and my symptoms are improving. Still very tired though..

Contentprof

Regular Member

Joined : May 2014

Posts : 412

Posted 6/14/2016 6:51 AM (GMT 0)

For what it's worth, I've had severe extended UC flares (lots of inflammation & bleeding evident in colonoscopies) and yet no elevation of either sed rate or CRP. My docs say that's the case for some of us.

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