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Angioedema hives on arms, face, and genitals one week after remicade infusion?

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Ulcerative Colitis
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Posted 3/22/2017 6:36 PM (GMT 0)
Just restarted remicade and about one week after my second infusion i broke out in angioedema hyves all over my genitals, arms, and face. I itch all over and tried benedryl, a steroid shot, and benedryl lotion without any success. My rhumatologist said he's never seen this before but wanted me to continue infusions but at a slower rate. I'm not thinking it's a good idea, but was wondering if anyone else experienced this but was able to control it with some type of allergy med so they could continue infusions?
Posted 3/22/2017 7:50 PM (GMT 0)
I'd mention your reaction to the nurse who administered your remicade infusion.

How soon did the rash appear? Has it gone away since?

Did you take any premedications before your remicade? Often an antihistamine like benadryl or claratin is taken prior to the infusion, and they help reduce the likelyhood of an infusion reaction (any reaction happening within 48 hours after your infusion). If you've previously had a reaction to remicade then they may give you IV steroids as a premed, like solumedrol.
Posted 3/22/2017 8:49 PM (GMT 0)
Just curious - did you have angioedema prior to this?
I have a close relative that has this condition (along with a multitude of other auto immunes) and he can't work due to his condition is so bad. He's been to specialists, Mayo, tons of Doc's, has to carry epi-pen, and has had numerous throat closings which led to a lot of ER visits. He rarely ever achieves remission from it, its horrific for him.
Your mention of this just sent up a huge red flag because of my loved one.
Posted 3/24/2017 2:22 AM (GMT 0)
Thanks for the replies! Yeah, I received premeds before the infusion a short acting and long acting antihistamine. My didn't appear until a week after the infusion. It's been three weeks and seems to be getting worse. Steroid shot, zyrtek, and benedryl don't help at all. The infusion nurse never heard of anything like it especially a week after infusion. I've never had angioedema before in my life this is the first time. I'm sure my body is rejecting the remicade and this is the reaction and im probably just gonna have to move on to the next biologic.
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