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Ulcerative Colitis
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Posted 6/9/2017 12:15 PM (GMT 0)
Hi everyone,

I was just reading up on FMT on this forum and was wondering if you guys would recommend me to try it.

I've been taking quite abit of antibiotics for acne since when I was a teenager and I believe that may have been the cause of my condition. If I were to do this, I would get the stool from my brother as he does not take antibiotics, very rarely if ever, for his acne, unlike me.

Thanks!
Posted 6/9/2017 12:19 PM (GMT 0)
try it -
Posted 6/9/2017 2:46 PM (GMT 0)
FMT is like every UC treatment, works for some and not for others. There are no guarantees in life and especially in UC.

If I were to consider doing a FMT, I would prefer a clinical setting and I know there are plenty of trials going on at thee moment reguarding it.

/clinicaltrials.gov/ct2/results/map?term=fmt

There's folks who do home FMT as well. If that's something you can stomach then there's always that as well/
thepowerofpoop.com/
Posted 6/10/2017 1:25 AM (GMT 0)
I would definitely give it a go, particularly since it's your brother so his bowel flora may be able to restore something that you have lost with the antibiotics and you also have that permanently available and low-cost should it work for you. Just make sure that you get him thoroughly screened.
Posted 6/10/2017 4:37 AM (GMT 0)
Im trying it at fivedock in Sydney Australia. Dr brodys team..
Been putring it off for a while now and gonna try it before i try remicade.
Nothing to lose except $$ but nothings worth more than health.
Posted 6/10/2017 9:14 AM (GMT 0)
Thanks everyone for the replies! I'll ask my doc and see obtain her opinion on it. After seeing mixed results with imuran, I'm starting to feel that medications aren't necessarily the go to method, especially if I have to keep taking stronger medication. I'll post an update if I get this passed by my doc!
Posted 6/10/2017 12:26 PM (GMT 0)
And don't entirely write off the imuran. Literaly everything uc-related is mixed results.
Posted 6/10/2017 8:19 PM (GMT 0)
I'd try it, but I didn't when confronted with surgery or do an at home FMT (there weren't any trials available that I was aware of at the time). I agree with iPoop, i'd prefer to do it through a trial than do it at home, but I wouldn't discount either option, people have had luck with at home. I personally got to the point where I wanted something that would put an end to UC. I never felt that medicines were the "go to", but they were the only things that ever made a dent. Unfortunately, they didn't work well enough to keep my condition stable.
Posted 6/10/2017 10:56 PM (GMT 0)

UCdude said...
Thanks everyone for the replies! I'll ask my doc and see obtain her opinion on it. After seeing mixed results with imuran, I'm starting to feel that medications aren't necessarily the go to method, especially if I have to keep taking stronger medication. I'll post an update if I get this passed by my doc!


i'm pretty sure you're aware of this, but, you don't need your docs permission to put your bro's poop up your butt -
Posted 6/10/2017 11:50 PM (GMT 0)
The turd is right. Might as well just go for it!


I was just reading an interesting piece where the topic of FT was touched upon:

Somebody said...
G&H Will the gut microbiome play a role in future treatment for inflammatory bowel disease?

WS It may very well. It is clear that fecal microbiota transplantation is an effective therapy for recurrent Clostridium difficile infection. Research is currently being conducted to see whether that effectiveness carries over to inflammatory bowel disease as well. The results of a study on fecal microbiota transplantation in ulcerative colitis were presented at the 2016 Digestive Disease Week. Using multiple donors, the researchers pooled together stool and administered multiple fecal transplants over a period of months. Such an intensive regimen may not be feasible in clinical practice, but it did provide benefit to the patients, giving the procedure some proof-of-concept. In contrast, studies of single fecal transplants from individual donors have been much less effective in patients who have ulcerative colitis.

In the future, there will likely be additional controlled trials with microbiome products, whether stool or microbiome-oriented products. Although I do believe that the concept has promise, there is still much to be done to figure out an accessible and practical regimen to study, and we are far from bringing microbiome products into routine clinical practice.

www.gastroenterologyandhepatology.net/archives/july-2016/the-present-and-future-of-inflammatory-bowel-disease-treatment/

Posted 6/11/2017 10:14 AM (GMT 0)
Very good read (link above)!
Posted 6/11/2017 11:26 AM (GMT 0)
Your brother, excellent!
Posted 6/11/2017 1:01 PM (GMT 0)
Try it but you should still have his stool sample tested to make sure he doesn't pass something on to you. I recently read one study where patients who did not respond to conventional treatments, including biologics, had an approximate 25% remission rate with FMT (I am reciting this from memory, do your own research.) This is pretty impressive, IMHO, considering these patients' only option left was surgery.

I do not recall the sample size but the interesting thing was that almost all patients who achieved remission had received a transplant from the same donor. They used 4 different donors for the trial. I am interested to see how doctors and scientists are able to screen donors for beneficial strains of bacteria, etc, going forward.
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