Posted 8/14/2017 1:53 PM (GMT 0)
Take all of you pred first thing in the morning as it helps reduce insomnia at night, and mimics your bodies natural cortisol mechanisms better. Prednisone is synthetic Cortisol. Your body has the very highest levels of cortisol during the early am, in fact cortisol is much like an alarm clock that wakes you up in the early morning. Your body's cortisol levels then naturally fall throughout the day and are at their lowest when you go to bed and are asleep. Take Pred before bed and you'll have a loud alarm clock ringing all night long and get no sleep, insomnia like crazy!