This would explain why medical marijuana works so well for certain people, including digestive conditions such as IBS and IBD.
/www.ncbi.nlm.nih.gov/pubmed/18404144CONCLUSION:
Migraine, fibromyalgia, IBS and related conditions display common clinical, biochemical and pathophysiological patterns that suggest an underlying clinical endocannabinoid deficiency that may be suitably treated with cannabinoid medicines.