Anyone's tried this

I have been diagnosed with sever Pancolitis since July-17.
Am on 3600mg of Asacol, .75 mg of Aziothiprine (imuran) and Predmed-16 mg a day

Was feeling much better when the Doc prescribed only Predmed-16 mg twice a day, but in a rush to feel better started taking 16 mg thrice a day, but no Azothioprine. My appetite was great, was eating well, started gaining weight, feeling of wellness improved drastically etc. I even started doing Yoga which made me feel better.

Then Doc prescribed Aziothiprine (imuran), and reduced my Predmed and my life started becoming miserable again and has reached to depths I can't imagine-my weight is decreasing daily, feeling progressively weaker and coming to trying to exercise-Pooh the thought itself makes me more tired

I am thinking of increasing my Predmed dosage again to 48 mg a day and reduce the Aziothiprine (imuran) to .25 a day and see what happens as I am really fed up of feeling this way. In the meantime I also plan to eat better and start Yoga ( I used to practice regularly) and start light weights. I just want to feel better again
HAS ANYONE TRIED THIS UNORTHODOX APPROACH...
Any advice or comments...anyone...pls

Pancolitis can often require much stronger medications like biologics (remicade/humira) and it might be time to try them. I think reducing your azathioprine/imuran is a bad idea and I wouldn't recommend it.

Remicade is the only medication to put my UC into a remission. I've experienced no side effects from it.

Thanks a lot for your inputs, Guys! Couldn't respond sooner.

I think, I'll tell my Doc to change the Imuran (Aziothioprine) to Ramicade/Humira and see what he says.

I just hope side effects of Imuran stops.