Antibiotics in IBD: Still a Role in the Biological Era?

Interesting. What would antibiotics be treating? Infections that are secondary/opportunistic within the UC patient? I know there's a couple posters over the years that said antibiotics worked for their UC when nothing else did. One had a loty of troubles after using a triple-antibiotic-cocktail themselves, as a potential treatment (more harm than good).

Well I have seen studies regarding viruses causing or contributing to resistant UC flares. Once anti-viral meds are given, the flare clears up. I'm sure bacteria can do the same. I am looking forward to more targeted antibiotic/probiotic therapies.

Genetic Biomarkers may predict response to QBECO therapy...this is interesting

[quote=]Genetic analyses found that response to QBECO treatment was associated with specific ulcerative colitis-related variants in regions of the genome close to genes of high relevance to QBECO’s mechanism of action, i.e., genes involved in the activation of innate immune function and clearance of bacterial infection/dysbiosis.
Taken together, data from Qu Biologics’ first clinical trial in ulcerative colitis contributes to our understanding of QBECO treatment and, potentially, suggests that it may be possible to identify specific populations of individuals who will most benefit from QBECO treatment. These results support continued development of QBECO for the treatment of ulcerative colitis.