HealingWell
Search Close Search
☰

FMT with my 8 month old as donor

Support Forums
>
Ulcerative Colitis
✚ New Topic ✚ Reply
❬ ❬ Previous Thread |Next Thread ❭ ❭
Posted 6/18/2019 5:18 AM (GMT 0)
Hello UC gang,
I am considering doing a an FT in the near future.
1.
Somebody told me that the best donor is a nursing only baby.
My daughter is now 8 months old and still exclusively nursing.
Anybody have any thoughts about this, or experience?
2.
If I take the feces from the diaper it will most probably contain urine.
Would this be an issue?

And yes, I saw the recent post about somebody dying from FMT.
My thoughts are that maybe my babies poo is really clean which would eliminate the issues.
Thanks.
Posted 6/18/2019 11:43 AM (GMT 0)
You can try but it may not help as much. A significant portion of gut bugs are anaerobic in nature. Since her poop in the diaper will get mashed, more of these bugs will be exposed to oxygen and probably will die.

IMHO, the best way to obtain donor sample is to make the donor poop in deoxygenated saline but since that is not an option for a DIYer, just pooping in saline will give better mileage than using mashed poop.

Just my 2c.
Posted 6/18/2019 1:14 PM (GMT 0)
I agree about less exposure to air by having poop drop into saline ASAP.

Also, whoever told you about baby poop is uninformed about FMT. A child that age will not yet have a fully populated gut microbiome. Some are obtained in uterus, and some obtained during birth. But most are obtained/grown during the first couple years of life. Your baby is shooting blanks.

good luck
Posted 6/18/2019 3:21 PM (GMT 0)
Lol "shooting blanks". Agreed, most sources say the microbiome isn't fully developed until about 3 years of age. At that point your child might be a suitable donor. And yes urine would likely be a problem so waiting until your daughter is out of diapers would be a good idea.

If you're really set on trying FMT I do agree your daughter would be a good donor (when she is a bit older) as you know her health history, and you have unlimited access to her fresh stool. Still worth doing standard stool tests before to be safe and letting your doctor know. Another note, recent antibiotic use (within the past 6 months) disqualifies donors from stool banks. So just be wary of that if your child has to go on antibiotics for an ear infection or whatever other common reasons kids that age need antibiotics, her stool wouldn't be prime for transplant until some time after.
Posted 6/18/2019 4:45 PM (GMT 0)
I agree with DB and Maria. While baby stool is relatively safe, it's supposedly not as effective. Actually, the best donor is someone who doesn't live in your household and has a lot of variety of bacteria in their stool - so, someone more mature. I have heard of people using their infants soon with good luck though, so I am not saying you shouldn't bother.
Posted 6/18/2019 6:40 PM (GMT 0)
Now that there is a little consensus, I would like to deviate from the thread. Few things you can do to improve your DD's overall health over the period of life, give particular attention to her exposure to various things (some known, some still unknown) until she is 3. Almost until age 3, the body is making a blueprint of various 'thing's', like gut flora, immune system etc. Most of it is still unknown and work is in progress to elucidate the roles further.

I understand what I have said is extremely vague, but you should research along these lines on what you find, what you are convinced with and what you would like to follow. Just a hint, the doctor doesn't know the best. All I can say is, try to live life as your great grandparents lived (food, lifestyle particularly).
Posted 6/18/2019 8:01 PM (GMT 0)
Hi... I took part in an FMT clinical trial last year and I am also part of a big focus group on this subject.

Stool from infants is not appropriate because it contains only basic spectrum of flora. As infants explore the world and put things in their mouths to obtain new flora and this trains their immune system. This process takes years.

Stool from an infant in your family is even less effective because they will be inheriting the same microbiome from you and your environment, especially if you birthed them vaginally.

about 1 in 10,000 adults is an appropriate donor. The doctors in my clinical trial took 5 years to select 1 or 2 candidates from a pool of 2,000 volunteers. They screened their stool once a month for 3 years and followed their lifestyles closely. These people have always lived in the same place, never travelled, never had GI illness, never did antibiotics or vaccines, never had surgery, never spent time in high risk hospital zones, have perfect diets, etc. Once they obtained those 2, one person dropped out of the program for unknown reasons. Now they just have the 1 person.

If you want to do FMT you're better off going through a lab that specializes in it.
Posted 6/18/2019 9:32 PM (GMT 0)

MarkWithIBD said...
The doctors in my clinical trial took 5 years to select 1 or 2 candidates from a pool of 2,000 volunteers. They screened their stool once a month for 3 years and followed their lifestyles closely. These people have always lived in the same place, never travelled, never had GI illness, never did antibiotics or vaccines, never had surgery, never spent time in high risk hospital zones, have perfect diets, etc. Once they obtained those 2, one person dropped out of the program for unknown reasons. Now they just have the 1 person.

Hi do you know the name of your clinical trial? I'd be interested to read more about it. Thanks.
Posted 6/19/2019 12:14 PM (GMT 0)
Yissutim , I just did my first FMT in the hospital Monday , it’s all screened in Winnipeg, Canada . And I had no issues . We are trying to treat my pouchitis so it’s a bit different then your issues .
You mentioned someone died from FMT was that on this forum ??
✚ New Topic ✚ Reply