Something new on Crohn's and UC

Very interesting. Thank you for sharing. There might be similar mechanism in UC.
Resistant bacterias can create a biofilm on the surface of bowel mucosa and our immune system attacks them.

Nope.Every once and awhile I pop in, if I find something of interest.
In the 2nd article on UC looks like IFN-Gamma is a problem. Perhaps Berberine will
inhibit.
Oldmike

Thanks for posting this. I have wondered for a long time why the bowels of UC patients are so friable and this is one explanation. It's like blood vessel integrity is just garbage.

I also suspect that micro-circulation is a problem for UCers. I thought this because last year working with an osteopath helped get me out of a 2 year long flare. She found that my mesentery was twisted and I was having sub-optimal blood flow to my left colon. I'll never forget... after my first appointment I bled profusely the very next day, and then all bleeding stopped and I started healing.

I think if blood flow is sub-optimal, then intestinal cell turnover will be slower and less resilient to environmental impacts. I really do wonder if some of us have sub-clinical bowel ischemia. Not true ischemia, but a light version. If blood flow is poor then blood vessel integrity will also suffer and that's when the bleeding happens. Then once the vessels break, bacteria get in and you get localized infection.

Unfortunately modern medicine is not keen on visceral manipulation or optimizing blood flow. They look for real ischemia. They don't care about things like fascial displacement. I really wish the different health professions could work together. The shared knowledge would be incredible.