rowasa causing a flare?

...so I was tapering from steroids and things were going well, but i've had problems in the past tapering, and so my doc gave me a prescription of rowasa to have around just in case. normally I'm on colazal, and have never taken rowasa or any enemas before. When I got back down to about 5mg of pred a day I was starting to feel some of the effects of colitis creep back in...nothing terrible, just a little softness in the BMs and very mild urgency. I figured what-the-heck, I might as well try the rowasa....

well, after about 4 days it felt like all the colitis effects had RUSHED back--urgency, loose, unformed BMs, cramps, pain, nausea.... I decided to skip a night of rowasa (last night) and see what would happen. today I had mild urgency in the morning...but otherwise I've felt MUCH better. some symptoms are still there. though much milder..and there's absolutely no cramps or pain.

anyway...has rowasa, or high doses of mesamaline triggered colitis-like symptoms in anyone else? Is there a ramp up time that I should suspect for rowasa and those effects go away? Should I continue to NOT take it until I can talk to my doc, or should I take it and feel sick till then?

yep, i retained it all night each time. I administered the rowasa and didn't 'expell' anything until the next morning. I would get cramps throughout the day--but mostly in the morning. by nighttime i usually felt ok again.

and yup, im still on colazal too..

And while, yes, I was technically tapering pred, I actually was between 'steps' and on a steady pred dose. for me, the effects of a pred dose drop only really hit the day after, and then level off--then, once a week or two had passed, I drop off again. I was near the end of that second week, about to drop again, when this stuff happened--so that's about as small a factor as it could be, i imagine.

i mean..the contrast was pretty sharp--the first day after i took rowasa i was feeling bloated and 'icky'. the second day after I felt a bit cramped, in pain, etc...it was a pretty stark, and sharp, decline.

I didn't take it last night either--and now i feel great! no colitis symptoms all day, so far... what the heck is going on with me?


anyway, thanks for your thoughts--if the doc suggests i keep on it, i might bring up the 'skip a day' thing

Old Hat, by sulfites do you mean sulfa? (I'm allergic to sulfa which could explain what I mentioned below)

I too can't do Rowasa because it makes my symptoms 10xs worse and not to mention it makes me feel like I have the flu. I tried numerous times and each time it made me feel horrible. So both me and the GI came to the conclusion that I was in the small percentile that can't tolerate them.