It sounds like you have a pretty good handle on UC, but you might do better on one of the other oral 5ASAs. Also, it would be better to see your gastro at least twice a year. Are you having bloods & urinalysis tested by other docs regularly? Gastro should also be paying attention to those to monitor your level of inflammation & effects of meds you take, plus any vitamin/mineral deficiencies that could impact on UC. It doesn't seem like you need to go on immunomodulators from your descript
ion of symptoms to-date. As Quincy writes, some change in your 5ASA usage might get you more consistent results. / Old Hat (nearly 30 yrs with left-sided UC; currently on 3 Colazal daily for remission maintenance)