I too have had the throat problem while on Zantac, Achiphex, etc. It seems these drugs can cause Rhinitus. I found that by drinking a lot of water and using saline solution sprays (in the nose) that it helps. I will also go off the drugs, for a period of time, to help lessen the problem. Do you find it is better first thing in the morning? I have had other side effects from Achiphex, protonix, nexium, etc. I am hypoglycemic and these drugs cause my blood sugar to drop way to low causing; palpitations, anxiety, pulsing in my ears, raised blood pressure, etc. Those drugs also have a histamine blocker. So, if you have a problem with that you can also have more side effects like myself. The combined side effects,from those drugs, was worse then the reason for taking them. So I have had to go back to taking just Zantac. I was finally refered to a specialist, recently, about my stomach pain. He said that what I told him sounded more like an ulcer then reflux or gerd so he is ordering more tests. Isn't it funny how the docs will throw tons of meds at reflux or gerd but refuse to try meds for an ulcer until you've had a ton of tests?