Low grade nausea for the past 2 years. Ideas?

I have a low grade dull nauseous ache in my entire gut that can't readily be attributed to anything, after a series of GI and other tests. It started a couple of years ago, while on PPI therapy for GERD and though my PPI has been changed and even paused for a week, the discomfort still remains.

Some days are better than others. I am on a GERD diet - that is, without trigger foods.

Anyone experiencing this?

Many thanks,

GM

Thanks for responding.

Here is how it all came about. Around 2+ years ago, I started getting sick, as in nausea, chills, vomiting, diarrhea when I would eat out at various restaurants. At first. I thought it was coincidence. It was all intermittent until last year when I became sick again only after eating out. My docs thought that the PPI (Protonix at the time) was making me more susceptible to gastric infections - see here:

https://www.healingwell.com/community/default.aspx?f=45&m=2672535

When I "recovered" from the last two bouts of this "symdrome," I never felt totally well again. At that point I was switched to Dexilant, 60 Mg, QD due to the GERD after another round of esopageal manomety and pH/impedence testing indicated that I needed a stronger, longer lasting,  PPI.

Something was making me feel lousy, leaving me with a low grade, dull, nauseous ache in primarily in the lower abdomen. I still have an appetite, but really just want to lay in bed. I have had an upper and lower endoscopy, MRI enterography, stool samples, among other tests which came back totally normal. No h.pylori or c.difficile.

The only thing that came back positive was a hydrogen breath test for small intestinal bacteria. I was placed on a very potent (and expensive!) antibiotic, with no luck. In time, the nausea reduced and I went on with my usual daily life and just waited for the day to end so I could crawl into bed.

2 weeks ago, the discomfort became somewhat more pronounced, for no apparent reason. I have not been dining out and have been watching my diet so as not to introduce trigger foods, as mentioned above. My doctor prescribed 8 Mg of Zofran PRN and that really did not help much, so I stopped it.

Very weird. I just feel lousy and can't pinpoint the cause. My GI doc is smart, but on this aspect, clueless.

I will call him again, but I just want to see if anyone else is going (or has gone) through this.

GM

Some medicines have specific instructions about how to take them. This is because they work better when taken correctly. These instructions can include getting the right dose and special instructions for preparing the medicine. Make sure you follow any specific instructions given to you by your prescriber or that are in the Patient Information Leaflet that comes with this medicine.

If you are having problems taking this form of Zofran, you should talk to your prescriber . They may be able to give you advice on other ways to take your medicine or other preparations that are easier for you to take.

Also there are other choices and what worked for me was Compazine throughout my  chemo. JMHO

Sorry to read you are feeling nauseated as I know that is miserable.

Kindly,

Kitt