Posted 1/1/2014 4:47 PM (GMT 0)
Sometimes I get a problem when I think that my PPI has stopped working properly. I put this down to my digestion, sometimes the uptake is good, other times not so good. This has an effect on the efficiency and speed of the inhibition of the proton pumps.
From what I have read, an individual dose is active for up to 16 hours, with the action reducing over this period. Some acid production continues at a low level during this time.
Altering the time of day of dose, or breaking the dose into two portions a day are useful strategies. It may be worth trying increasing the dose, subject to confirmation from your primary healthcare professional.
Cheers
Phil