Hai Hai,
Good Morning. Weight gain is not a common side effect of Nexium (esomeprazole). According to the prescribing information for Nexium, weight gain was reported by less than 1% of patients in clinical trials. Consult your healthcare provider for any changes in your medical condition, including unusual weight gain. Do not stop or change the amount of medication you take without talking to your healthcare provider first.
Kindly,
Kitt