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PPI's and Heart Disease

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GERD & Acid Reflux
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Posted 9/12/2013 4:10 AM (GMT 0)
Unfortunate new study..

Acid Reflux Drug May Cause Heart Disease, Study Suggests

http://www.sciencedaily.com/releases/2013/07/130710114225.htm

Drugs that help millions of people cope with acid reflux may also cause cardiovascular disease, report scientists from Houston Methodist Hospital and two other institutions in an upcoming issue of Circulation (now online). It is the first time researchers have shown how proton pump inhibitors, or PPIs, might cause cardiovascular problems.
Posted 9/12/2013 5:32 AM (GMT 0)
:-( sadness
Posted 9/12/2013 8:32 AM (GMT 0)
PPis are poison .
Posted 9/12/2013 10:45 AM (GMT 0)
I don't know enough about those studies to make a conclusion, but it also states the following several times:
"Recent studies of proton pump inhibitors use by people who've already experienced severe cardiovascular events..."
So I assume the risk is a lot less if you don't suffer from a heart disease. I'm not gonna say PPIs are good, I'd rather not take them (or Domperidon for that matter, which can also cardiac problems), but what options are there? Taking no PPIs and develop cancer? Having a Nissen and potentially mess up your degistive system forever if the surgeon doesn't know what he's doing? Or maybe not improving at all in spite of having surgery (hello LPR!?)? Or needing one or several redos? Getting the Linx and never being able to have an MRI scan or not knowing whether it will erode or migrate over time? Live on rice, veg and steamed fish for the rest of your life, be underweight?
I guess it's always a question what is the lesser of two evils...
Posted 9/12/2013 5:49 PM (GMT 0)
Just to clarify IDAD, I have been told by numerous GI doctors that PPI's offer nothing but side-effects to those that do not have Barrett's, and to those with Barrett's, they are strongly recommended (although the benefit is modest).

I just want to make clear the truth against the misconception that PPI's are some great anti-esophageal cancer invention. They don't cure GERD, they cure sypmtoms. Obviously they have their place though.
Posted 9/13/2013 6:00 PM (GMT 0)
To add to the confusion, cancer of the esophagus has increased since PPI'S have come into use. There is some support for the idea that it is not the acid that causes the cancer.
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