I've had reactions to many medications, but never to Zoloft, I know all our bodies are different and respond differently to medications.
I just got back on Zoloft, so because I never feared that medication, I had no reservations in trying it again, and I started at 50 mg's this time.
When I did have an ALLERGIC reaction to a medication it was typically in the first 4 days, and mine was hives all of my body, or a reaction that you know is just not right.
I was just told to take fish oil by my doctor for my cholesterol, and I was scared of those, but am still here
I really understand your concerns, I am extremely paranoid of medications, but that is just me being me!