i have basically been on zoloft for about
9 years. i didn't start gaining until i had been on it for about
a year, and that coincided with leaving college and getting a desk job. i very quickly put on about
40 pounds. but i had been getting very little excercise and eating much more (pint of ice cream per night - no wonder!). after a couple years i went on weight watchers and was able to lose it all. i then got lazy and put it all back on and then some. i just started weight watchers again and have been able to lose about
6 pounds in just a few days and hope in a few months to get back to normal.
in sum, i did gain a lot of weight, but i really think it was more my eating habits and probably not so much a side effect of the medication. and you can definitely lose the weight while taking the medication (someone tried to tell me you would have to go off it or else you wouldn't be able to drop the weight).