TM.,
This is what I found on the Rxlist website. You should follow your doctors instructions of course. You should have been given a consult by him/her or the pharmacist.
The information below is just a guidline from a site.
If you have questions about your administration of your Rx call your doctor or pharmacist.Since it says to take with food...depending on if you are taking one or two pills a day...you will want to take around meal times. (breakfast or dinner) From what I have read, most people prefer to take their meds in the evening if they are only taking their pill once a day.
From the Rxlist:
The recommended starting dose for Effexor is 75 mg/day, administered in two or three divided doses, taken with food. Depending on tolerability and the need for further clinical effect, the dose may be increased to 150 mg/day
Best wishes with your start-up!
S.C.