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depersonalisation Effexor High dose

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Posted 9/17/2015 4:33 AM (GMT 0)
Hi there

Could really do with some advice. I have been on Effexor for 12mths for GAD mostly/depression going all the way up to 450mg, have been there for 6weeks. Im having a good couple of weeks then some anxiety/depersonalisation and the reason for the most recent increase was to knock off the PMS anxiety and any depersonalisation I have been getting .

I am functioning ok, working, family duties etc but I am not my usual confident self.
I just cant seem to get consistency and this actual last increase seems to be making it worse or at least symptoms/side effects coming more frequent. I have also been on seroquel for the last 3mths at 100mg which I have never had to take before and have been stable in the past on an antidepressant alone.

My thinking is, could the high dose actually cause the depersonaisation/anxiety as a side effect? or is it the illness?, the doc seems to think its the illness but I am not so sure, I am not in denial I just want to be careful because its such a high dose and I have had stability before at 150mg - 6 years and 300mg- 2 years.went off them to get pregnant.

I am seeing the Doc next Tuesday but just thought I would see if anyone had experienced this at such a high dose.

Thanks so much for your support.
Cheers
Tess
Posted 9/17/2015 7:55 AM (GMT 0)
Hi Tess

Sorry to hear you are having some anxiety/depersonalisation.

Do you see a psychiatrist? they are the best people to discuss medication issues with and are the experts when it comes to medication. 450mg is a very high dose so imo yes that could be causing you some extra anxiety but i'm surprised you have that as you are also on Seroquel which is very effective at treating anxiety.

Sometimes if you go off a particular medication and then have a gap before starting the same medication it is not effective as the first time round which is probably why you need a higher dose. It's important to remember that medication is not a cure all they will only help ease your symptoms so it's important to use all the self help you have to help manage your anxiety.

Keep us posted.

Hibee
Posted 9/17/2015 3:32 PM (GMT 0)
Tess,

Hibee has advised you well...so I have just my well wishes to add.

I hope you find the answers you need, and the balance with your Rx's that is just right for you to feel your best!

Keep us posted and we'll keep you in support.

S.C.
Posted 9/19/2015 4:54 AM (GMT 0)
Hi Hibbee

Thanks for the advice yes I am seeing a Pdoc and I understand that they know medication but I have been mostly struggling with the fogginess,depersonalisation and obsessive thoughts about how I am feeling, I am trying to just accept the thoughts as just anxiety but its been difficult to even concentrate.

I was thinking that the high dose maybe contributing to this as I have never been on such a high dose, we have upped seroquel to 150mg and although I am sleeping well and physically feel more relaxed I know I am just not right and its a scary feeling because its been such a long journey for me

I know I am much better then I was 12mths ago but I am still not getting consistency.
Thanks for your support anyway and hopefully we can find a solution when I see my PDoc on Tuesday.
Posted 9/19/2015 9:12 AM (GMT 0)
Hi Tess

I think it is something you need to bring up with your pdoc.

450mg of Effexor is a high dose especially along with 150mg Seroquel so I could see how this may be causing you side effects but remember I am not a doctor. I have been on high doses of psych medication in the past and have found it to much and have had to say to my pdoc that I want to reduce the dose or change to a new medication at a lower dose.

I hope your pdoc can give you some answers.

Keep us posted.

Hibee
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