Agreed, Rob. That doesn't necessarily mean there isn't some merit to the abx challenge theory. It is a cool theory, and there are anecdotes to support it, as well as credible enthusiasts. But it all...
My infectious disease guy treats all infectious diseases, but he's not IDSA, nor is he ILADS. He knows his stuff. But the politics can be threatening in Lyme world, so I understand where he's coming...
I have an infectious disease guy who takes my insurance, and he's good. But he prefers to play it safe, so he likes positives. I like to make him comfortable. Also, because it's a curiosity, at least...
I'm due for some TBD testing including all the usual suspects. I've been sick with the 3 B's for about a quarter century. I've been tested for Bb scores of times over the years. Historically Im CDC...
"it seems to me that the only way to uphold the belief that it does - would be to start with a belief that such practices were factual and then selectively sample the information landscape for half...
No, they didn't find new things in that region because that is where they looked. They found new things because there were three distinct outbreaks of diseases making many people sick with weird...
Garzie, let me see if I am understanding you correctly. Are you suggesting that because new microbes are being discovered ever day - and lots of them - that we should accept as SOP an unusual...
Great discussion. I will leave you with this question, Garzie: What are the odds that a non-testable Rickettsia would appear in the same area around the same timeframe as the Babesia you just...
Strains aside - and this is a huge aside - I would suggest that my Lyme disease does not manifest like it might have in my Grandparents. So trying to draw parallels with spirochetes from thousands of...
Sorry, Garzie, I forget how to cut and paste. Bear with me. I hear you about confirmation bias, and it's a two way street. You are right when you say we need to keep our eyes and minds open, and stay...
Garzie, remind me which Bb strains were in those three examples you cite from thousands of years ago? Relative to conspiracy theories, that's an odd phrase to throw about in the Lyme community....
Yes, Garzie, that's the one. Thank you. As you know, the ILADS community has discussed babesiosis as a parasite that can impact us systemically, across multiple organs, for years. It's not just a...
Peter Krause and fellow Yale colleagues just released a new retrospective on neuro-babs. To me that is significant even if it is a retrospective limited to acute cases. Cannot recall how to link to...
Anyone who is facing chronic long-term TBD's owes it to themselves to learn a bit about why we are where we are. To that end I'd recommend "Cure Unknown" by Pamela Weintraub, and "Lyme The First...
Brings to my mind Jen Brea's ME/CFS journey, but maybe I'm misremembering. I do that a lot. Good luck today with your neurologist....
Well, you're playing in the right ball field, as far as I'm concerned. Lol. I'd ask them - at the very least - to refer me to whatever lit is out there on low VEGF.. I'm assuming you've had brain...
Garzie, I sympathize with you. I've encountered that odd UK.....hmmm, what's the right words...arrogant ignorance? resentment? hostility??.... toward Lyme. I believe it's rooted back in the early...
So the NHS offers the C6 and the VlsE1/pepC10?? I cannot get my head around that. You realize there are different forms of the MTTT? There's some strange Lyme stuff going on. I think it's stranger in...
No worries. I used to know a thing or two about the C6 ELISA, but clearly I've forgotten. I've been tested many times on the same day with different labs, but they were always looking at the...
I am confused. The C6 comes from VlsE, It's just that peptide from that broader protein. Right? So now, for example, the MTTT players are in part looking at entire VlsE vs just the C6 snippet, like...
loski01, The C6 peptide test should have worked (or not) regardless of where you got it. I wonder if Immunetics made IGenex's for them? I cannot recall. But it's kinda like getting a B31 kit - same...
We are acute-centric as a society. It's shameful that we remain so considering the chronicity that is evident if we just open our eyes. So let them get off their backsides and take another long hard...
My infectious disease doctor checks my VEGF values at least once a year because he is wary about conventional bart testing. His logic, as well as others like him, is that high VEGF may be suggestive...
"....reduced VEGF levels cause neurodegeneration in part by impairing neural tissue perfusion..." This from a study entitled "VEGF; a critical player in neural degeneration" in The Journal of...
Not to be overly pessimistic but I think if you've any combination of the three B's, there is no easy fix. I know my symptoms could be attributed to babs or bart or Lyme, or any combination.. The...
Oh, what a cool thought. That' you know this is very cool. I worry about low VEGF values because of the correlation with neurodegeneration. My thought was perhaps low VEGF levels could be a marker of...
What kinds of results have members had when being tested for VEGF levels? I usually test out-of-range low. I'm curious about others. Obviously if you've bart you may test elevated. Do you test in...
Well, silly me, Girlie. Check virology 101. And I don't care who you quote: No one knows anything meaningful. Insert any name you want. Burrasacano was throwing darts. What we need to do is...
If past is prologue, we're likely to be disappointed....
Right, but not according to IDSA/CDC doctrine. All those studies from the '80's. We defy them....
No, that's not what I was saying. :But thank you for thinking of me. My values fluctuate, and I'm taking antigenic variation into consideration. Not just bands, but ELISA numbers. CD-57, too. This is...
Or forever quell the body's ability to produce measurable, i.e. a positive response, Bb antibodies. Weird paradoxical stuff....
There is no way to demonstrate if Lyme has been eradicated. None. But there are ways to nudge spirochetes to see if they're there. But those ways are unreliable at best....
Hello Fronton, Igg and Igm. For Lyme 2t and MTTT. For babs and bart just antibody testing....
Well, not quite accurate. There's an asterik with that theory - which was put forth back in the 80's when they couldn't have known - and the asterik is that values may remain positive, but should...
My infectous disease doctor likes to keep track. For instance, I used to test positive for bartonella. He treated that aggressively and now I no longer do. But my ID guy still checks, even via vegf...
I've been tested for Lyme at least 100 times. I've always been Elisa positive. Always. I recently got Covid. Was on paxlovid for five days. Five days later got tested for Lyme - and my Elisa was...
astroman: https://www.nature.com/articles/d41586-022-02286-7 This is a link to microclot stuff. The ME/CFS researcher tied to the long covid microclot efforts is Maureen Hanson,...
"I summarized it in my words. You can go google it. The doctor himself says 93% cure rate. And he defines what cure is it’s just like it sounds. This is over a period of 10 years just to make sure,...
"yes, exactly its possible there are some commonalities underlying some of these subsets though - they found borrelia in the brains of MS patients too - so was that involved in allowing the EBV to...
I think many if not most in the MS community learned what most of us were taught, i.e., MS is an autoiimune disorder. It may well prove to be one. But what many have forgotten is that 50 or so years...
Hey, thank you so much! :)...
I'm sorry but i cannot figure out how to copy what someone posts here. I agree with you. I actually have had this discussion over the years with peeps on PR and the UK forum as well. The same holds...
Garzie, so yes, I suppose progress is being made. As for bio markers, you learn to take everything with a grain of salt. ME/CFS is likely composed of subsets, much like it seems recently MS is....
Alleged cure. Purported cure. Cure du jour. I suspect anyone who says they've discovered THE cause of ME/CFS likely does not understand it fully. For the great majority of ME/CFS sufferers, there is...
Agreed. :(...
From what I can ascertain, the Brazilians used G39/40 antigens to help prepare diagnostics. They employed the 2T, which didn't always fail, just generally. Sound familiar? So they modified the...
Garzie, go directly to Section 4. Everything before that is a bit, imo, misleading. Keep reading through Section 7. Well, keep reading beyond even that. lol. But this is from Section 7: "Currently,...
Garzie, they are talking Bbss. It's Lyme, or a close facsimle. Think Masters disease and what the CDC did with that. Read the study. Forget the abstract. While you read, remember they were counseled...
Some snippets. Keep in mind this is Borrelia Burgdorferi sensu stricto: "B. burgdorferi, the etiological agent of BYS, can remain dormant for long periods of time (cases # 2 and 6) and progress into...