I haven't posted here in several years but was wondering if anyone is aware of any recent results on ADT3/Leibowitz' protocol (or similar) as primary therapy for localized PCa? I haven't found any...
Agree with proscapt and others about sun exposure issue. I was on 4000 iu through winter with serum D of about 65. I backed off to 2000 iu for summer to allow for sun exposure. My lab just came back...
By the same logic, one would expect recently reported AS studies (or any AS study) to have a similar percentage of understaged men among their participants. Yet there seems to be no greater risk (in...
This book just made it to my local library, so that might also be an option for old-school folks if you don't want to buy it. I placed the first "hold" on it so I should finally get to read it,...
Thanks for the link, Tony, it's an interesting case study. It would be interesting to know if Terry maintains the same perspective on AS today that he had 10 years back. I was surprised to read that...
Isn't it generally agreed that there is no significant survival benefit to treating Gleason 6 cancer until at least out 10-12+ years in time? My (rhetorical) question would then be what treatment...
Thanks for the discussion. I'm one of those guys on the fence. I'll definitely discuss with my doctor at my next visit. I'm not really troubled by a particular clinician not publishing studies, maybe...
Dana Jennings (NY Times) take on the book: http://well.blogs.nytimes.com/2010/08/30/a-rush-to-operating-rooms-that-alters-mens-lives/ ...
Thank you for that synopsis, John T. Just what I was looking for. I plan to purchase book and discuss with my doc. My doc is insistent that if I continue on AS path I need specific criteria that will...
Just curious if a coherent, systematic strategy emerges from all this for managing low-risk prostate cancer? Sounds like it is more hit-or-miss, anecdotal stuff? Not discounting that it's mostly...
I haven't got my book ordered yet, but I was just wondering if Scholz expresses any opinions on using dutasteride in low grade cancer? I get the impression that Myers favors using it with low-risk...
There is a "Mediterranean Food Pyramid" that gives general guidelines of what to eat. See, for example, http://www.safe-and-easy-weightloss.com/MedDietPyramid.htm "Moosewood Cookbook" is one of the...
Just wondering why folks go with DES vs. estrogen (or estradiol?) transdermal patches? I've read that some side effects might be lessened with the patch. Do they both do the same thing? I'm not...
Basically he says ketaconazole is an older drug, but can kill PCa by multiple pathways and may be worth trying in hormone-refractory patients before moving them on to chemotherapy. I usually watch...
Thanks for the clarification, John T. I was surprised when I saw that in the review. Maybe they are talking about Avodart/Proscar to block DHT instead of full-blown ADT3. Anyway, I look forward to...
from Publishers Weekly via Barnes and Noble website: "those who've faced any cancer crisis should also take heed--and heart--from cultural anthropologist Blum, who's lived with prostate cancer for...
Could try searching PubMed on "prostate active surveillance.....", etc. to find docs who publish on AS. Here's a fairly recent article with some big centers represented. I would think you'd have to...
I think the 70-100 range is recommended by Dr. Myers. I'm not sure of all the science behind his recommendation. I spend a fair amount of time outdoors in the southern US (without sunscreen, usually)...
Broccoli sprouts. Has something like 20-50 times the sulforaphane of mature broccoli. On a thread awhile back, it was mentioned that Johns Hopkins tried to patent them. Anti-Cancer Effects of...
Blend soy milk and/or soy protein with banana and frozen berries into a smoothie and you get your soy without even tasting it. I think Dr. Ornish advocates a low-fat vegan diet? I've tried vegan and...
Jim, There are a lot of Dr Myers' dos and don'ts in a recent link from zufus - www.prostatecancertopics.com/topic000.pdf The 3rd or 4th slide in this file shows a lot of his recommendations. There's...
Thanks for the link. A lot more detail on some of his ideas than I've seen elsewhere....
Dr Myers has a lot of info on his web site and blogs, prostateforum.com, I think. A recent newsletter describes his "Active Growth Arrest" protocol. It includes many of the supplements and dietary...
Are you a mad scientist at your day job too? Here is another HIFU application you might be interested in... not actually heating tumors, just shaking them up. Here's a report on it from DUke Univ....
That reminds me.... I saw in one of Dr. Myer's blogs that he recommends not taking your Vitamin D with oatmeal (which I was doing at the time). Apparently the oats bind the Vitamin D and so limits...
Link is not working for me, but I'm on the same JHU email list and here is an excerpt: "While no animal studies I am aware of show complete cure of prostate cancer with vitamin D therapy,...
Thanks for the link. I always assumed the Gleason scale was the same today as when it was first introduced; interesting to know it was 'tightened up' on the 3's in 2005. Appears to add another layer...
If PCa mortality really is increasing, I would think the "obesity epidemic" of the last 20+ years is a significant factor. A link between obesity and PCa mortality has been demonstrated:...
Follow-up from JHU.... "Delay In Surgery Not Likely To Worsen Tumors In Men With Low-Risk Prostate Cancer"...
I'm not sure about JHU study, but this is a direct quote from Beth Israel Deaconess study I linked to previously-- "We observed similar rates for development of metastases (n = 20 and n = 199; 7.2 v...
Just wondering if folks have seen any scientific, documented downside to AS in low-risk prostate cancer? I hear the downside from my docs, but haven't seen it in any recently published studies that...
I'm all for non-invasive, so sounds good. I'll sign up when you get to Phase III trial!...
Jeff, Mayo Clinic has a page on RF Ablation for Cancer using a needle-probe type device. Only appears to be used for liver, lung, kidney and bone cancers....
I believe hazard (ratio) refers to the relative risk of dying from something else. Earlier in the article they mentioned the men in the study were 19 times more likely to die of something other than...
From James C's link, it seems to me that the actual HIFU treatment arms of the trial are closed (have reached full enrollment) in the US, and are not yet recruiting in Canada. Only the brachytherapy...
Might consider almond milk too. It seems widely available now. I use both soy and almond milk, but prefer the taste of unsweetened almond milk over soy. Sometimes I mix them to use in smoothies, etc....
I think Dr. Ornish at UCSF has done some pioneering work in this area. Might want to look for some of his studies. Here's an excerpt from his WebMD bio: "He directed the first randomized, controlled...
I wasn't interested in participating in the UCSF/Provenge trial, just curious if anyone had seen/heard if they were seeing a positive response from it....
According to WebMD link above, some guys are seeing years of survival benefit, so it seems as good as chemo on average and possibly much better with less side effects. Dendreon's website states the...
Ok, I still have CNBC on. If anyone is interested they're supposed to have Dendreon (Provenge-maker) CEO on tonight at 5:00 Eastern....
CNBC reported $31,000 per treatment, with 3 treatments needed over a month or 6 weeks, so total cost ends up $93,000. I'm curious if they released any info on how the treatment was working in men...
Thanks for the welcome. I'm mostly past the scared-out-of-my-mind phase now, though it still pops up from time to time. I've talked with several docs about different treatments, but haven't pulled...
Thanks for the info. It will be interesting to see how Provenge works in men with intact prostates. I wonder if they have any early results from this trial yet. I noticed the trial excludes men who...