Mumbo, yes PSMA scan back in 2014 when PSA was 0.8 was negative. Psa scan in June 2020 (during drug holiday) was also negative. How do you check if your cancer expresses PSMA?...
Diagnosed in 2010, surgery in 2011, PT3b. RT in 2012. PSA recurrence in 2014, PSMA scan negative at PSA 0.8. Treated with Casodex since 2014. Drug holiday since Sept 2020 (18 months) and continuing ....
Dx 10 years ago, had surgery and radiation therapy. Path report showed Pt3b, SVI, gleason 8 with tertiary 5. Psa recurrence 5.5 years ago, treated with only Casodex since then. PSMA pet scans at time...
George, very interesting approach How long have you been doing this? What is the daily bicalutamide dosage?...
George, how long is the bicalutamide holiday? What are the targeted PSA levels?...
George, thanks. So if these markers are within the ref range and stable, PSA is low and stable, then can we say that the disease is under control?...
Logo, I'm doing fine with casodex monotherapy and don't consider change the current treatment until it fails. This is my MO's recommendation too. I agree that no scan will show anything at this PSA...
Alephnull, My disease is under control with Casodex only since recurrence (5 years ago). What would be the benefit of adding Lupron?...
I had surgery in 2011 and adjuvant IMRT to prostate bed in 2012. Pt3b, Gleason 8 (4+4) with tertiary 5. Psa recurrence 5 years ago, PSA rose from nadir 0.003 to 0.8. Treatment with Casodex since...
I'm on Casodex mono therapy for almost 4 years. Current dose is 50 mg tablet every 3 days (10 tablets every month). Recent PSA is 0.25 and testosterone 307 ng/ml. SE's are gynecomastia and decrease...
https://www.int-imm-foundation.com/en/your-diagnosis/your-diagnosis-prostate-cancer.htm...
Hi Farz, Don't know the price of Xtandi in Iran but it could be cheaper in Turkey. The retail price of Xtandi 40 mg 112 capsules in Turkey is around $2,100 at the current exchange rate. There may be...
Hi GE, the only side effect of tamoxifen in my case is that it caused a decrease in my testosterone level....
You can take Tamoxifen 10 mg or Raloxifene 60 mg daily to prevent gynecomastia. Tamoxifen 20 mg daily may even reverse gynecomastia at the beginning....
Teddy9, Yes I do take ER antagonists to prevent gynecomastia. I started with tamoxifen 10 mg daily, it worked for preventing breast tenderness and swelling but it also caused o continuous decrease in...
Rust, I wouldn't recommend orchiectomy, it's irreversible. PSADT of 2.5 months is short but if your body responds to HT, it is not important at all. 3 years ago I had PSA recurrence and the PSADT was...
Teddy, I was on Lupron for 13 months, between May 2011 and June 2012. My surgeon was also Dr Tewari. I had IMRT at MskNY in 2012. 3 years ago my PSA rose to 0.8, at that time I had a Ga68 PSMA PETCT....
Hi Teddy9, I highly recommend Dr. Scher, he has vast experience in pc and can offer you some "crazy" treatment alternatives. Following recurrence almost 3 years ago, he has been treating me with...
Thanks Beth :) Lowroad: Casodex increases the testosterone levels. In order to prevent breast tenderness and swelling, I use tamoxifen but in my case tamoxifen has an adverse impact on testosterone...
I am on Casodex mono therapy for the last two years. In order to prevent gynecomastia I am also using Tamoxifen. Tamoxifen works well to prevent gynecomastia but has a side effect of significantly...
Pharmacies are not allowed to export pharmaceuticals. I've not heard any pharmacy having an online international order system...
You can buy the original product in Turkey at relatively cheaper prices. Xtandi is imported by Astellas Pharma under the same brand name. Here is the link to Xtandi retail price in Turkey....
Allen, what you wrote about how metastasis work makes sense. However, among the billions of cancer cells traveling in the blood stream, some metastasize and grow in some parts of the body. Could...
Your cancer is aggressive, I think you should not ignore it. You can try antiandrogens (Casodex tablet) with minimal side effects...
I agree with what TA said but I understand you peanut, because I'm like you too. I also want to get educated and prepared when there is no time pressure so that if and when it happens I'll not panic....
Hi Yank31, Are you taking 50 mg Casodex daily?...
Please see the attached graph showing blood test results in 2016 https://www.keepandshare.com/doc20/11160/blood-test-results-august-2016-pdf-94k?da=y ...
Hi Peanut307, I have been on Casodex mono therapy for the last two years. In 2014, when my PSA started to rise, my MO started with 150mg daily Casodex and PSA dropped from 0.8 to 0.02 in a month....
I had the CTC test and the result is zero cells. I know that results below 5 indicate a better progression free survival. My question is how reliable is this test, does it have a prognostic value? My...
A promising new test is for detecting prostate cancer more precisely than the current PSA test...
You are right Allen, Howard Scher is my MO....
While reading a discussion on another thread about Allen giving advice to another patient; I realised that I've never thanked Allen publicly on HW. As you can see from my signature I have an...
Hi Tahoe J, I have been on Casodex monotherapy with 50 mg daily since December 2014, when my PSA hit 0.8 My PSA dropped to zero in 1-2 months and stayed there until December 2015 when my doctor asked...
Thanks Allen. How important is it that the size of lesion increased from 1.1 to 1.8 cm in one year?...
Hi, A friend of mine has PC diagnosed 5 years ago. He is gleason 6. He had MRI and biopsy one year ago; MRI showed prostate volume 79.5 ml and one 1.1 cm ill-defined lesion in the right posterior...
Hi Yaamba, A friend of my mine, who was dx in 2011 and treated with surgery had a PSA recurrence last year. He is a Pt3b, Gleason 7 tertiary 5. His PSA rose from 0 to 0.86 in six months. He had the...
Please read the below links. Heidelberg and Munich Universities are experienced with treating advanced prostate cancer patients with radioactively labeled PSMA-617.This treatment is still...
My doctor at the MSKCC asked me to participate in a research study called "tumor genomic profiling in patients evaluated for targeted cancer therapy". They will look at the gene mutations in the...
Baptista, My MO gave a break for the cancer meds and wanted to see if the decreasing testosterone is the result of Casodex/Tamoxifene or the IMRT I had 2 years ago...
Hi Baptista, You do not have an aggressive cancer, I believe gleason 5 is not aggressive at all. Anyway, how were you diagnosed with micrometastases in 2000? What imaging techniques were used? I hope...
Peanut, My MO is a very well known expert in the US in treatment of advanced pc....
Peanut, I was on Lupron 4 years ago and for me the side effects of Casodex are much less. My libido decreased but I can still have erections without meds. Tamoxifen will prevent gynecomastia and...
Allen, Thanks for your comments. I'm taking Tamoxifen 10 mg to deal with gynecomastia and it's working. I think I have fewer se's with Casodex, sexual potency is ok, no loss of body hair, muscle...
I'm a pt3b gleason 8 with tertiary 5; surgery and IMRT following surgery failed, biochemical recurrence occurred last year. My doctor, a well known MO from NYC (specialised in PC) put me on Casodex...
No, I guess my situation was PSA recurrence without mets. PSA at that time was only 0.8. I was told that this test can detect lesions as small as 1 mm....
Mal, Yes I had it one year ago. What do you want to know?...
Can only share my experience. I had IMRT, 40 sessions to prostate bed and lymph nodes, total 72 GY, in early 2012. My RO was Dr. M. Zelefsky of MSK NY. I had 8 ounces of water before every session...
Hi Digger, Review my signature, I'm almost a G9, had robotic surgery and adjuvant RT and HT. I am 61 years old and still have a satisfactory sex life without meds. If you are not so lucky, there are...
Another T3b here...
I am an international patient and been treated in NY for the last 5 years. Currently H. Scher is my MO, he is a very nice person and he has a good reputation. He is flexible and accepts communication...