Farz53-- do you know what the dosage of your fathers prescription is? Is he taking a generic form? A study was done that showed taking 1/4 of the dose of zytiga with a low fat meal had the same...
There are several studies that report improved outcomes (longer survival) if the primary tumor (prostate) is treated (RT or RP) despite the existence of bone mets. I understand that some health...
Mattamx, do give careful thought to the studies that have reported on limited survival benefits of chemo for low volume mets. The recent STAMPEDE trial reported decreased progression (based on PSA)...
until Zytiga was (finally) covered for my husband, we had to buy it ourselves. He took 1/4 of the dose with a low fat breakfast as per a study that was done that reported a similar effect. Of course,...
Hello carattop. I'm so sorry about your husband's diagnosis, especially at such a young age. Do you mind if I ask where the cancer had spread given his T4 label? Interesting about the chemo when you...
My husband's pathology is similar to yours. I would feel that doing nothing for a month is letting a G9 tiger loose from his cage. Surely these scans can occur more rapidly....
What confuses me about what your MO said was that I understand that chemo is optimal for high volume mets. It doesn't seem that you've had imaging to know about mets. Here is a brief summary but the...
Thanks so much for your response JNF, Fairwind, Michael_T, John, RobLee, Redwing and Tall Allen. Redwing, your experience has certainly encouraged me to ensure my husband takes something, although he...
Here is what Dr. Nicholas James, lead author of the STAMPEDE trial wrote about Abiraterone/Zytiga for non-metastatic patients: The STAMPEDE study included more than just men with frankly metastatic...
A new article just came out: Bone Health and Bone-Targeted Therapies for Nonmetastatic Prostate Cancer: A Systematic Review and Meta-analysis https://www.ncbi.nlm.nih.gov/pubmed/28785760 My husband...
Tall Allen, From where are you obtaining the information in the STAMPEDE article that the men on the Abi arm died at the same rate as those on the ADT arm?...
Actually TA, it is progression-free survival that matters to us. I do understand population data and my husband has a very bleak prognosis, thanks to the GP not screening, a bad surgeon and low dose...
Thanks for your contribution Compiler. How long have you been with Dr. Lam and what was your status when you first started? Have you seen Dr. Lam since the Zytiga study came our and if so, have you...
Thanks for your response Michael_T. How long did you take Zytiga for? Tall Allen, thanks for your comment. Were Michael_T and MsWorryWart part of a clinical trial with Schultz/Lam? If so, I didn't...
If I understand correctly from an old thread on HW that I found, Schultz/Lam at Prostate Oncology Specialists have been prescribing Zytiga for hormone-sensitive men since 2012...
Starfinder, In answer to your questions: I think primary treatment might not be offered if my husband progressed to develop visible mets because the benefit of this treatment is not evidence based...
Starfinder, I've thought about this issue a lot. We are paying out of pocket for Zytiga so it wasn't an easy decision. I'm not sure if my theories are correct, but here they are. 1. There seems to be...
Yes, even if your PSA rose after a year and you are following rigorous D&E, you'll never know if it might have begun to rise after 3 months if you hadn't done anything. I think there's a...
Bobby Mac, I've met a few guys in the US who have had Zytiga covered in your shoes. In Canada, if you're lucky to get the prescription, it's $50,000/yr. It's reassuring to read that your MO was all...
Naples, I'm glad you asked this question. My husband has just completed aRT and will be on Firmagon + Zytiga for approximately 2 yrs. I wondered why-- do the effects of radiation harmonize with the...
We requested genetic testing and it was done, using my husband's blood. Her was tested for germline (hereditary) mutations like BRCA 1/2 and about 10 others. Fortunately, all negative. I understand...
Jannett, I'm very sorry to read that you'd dad's cancer is so aggressive. Has he had any genetic tests done? Would you mind sharing with me the cost of generic Zytiga in India? We might have to pay...
Two trials recently published reported significant progression free and overall survival benefits for newly diagnosed metastatic and high risk/local spread men who add Zytiga to long term hormones....
Snowcake, I'm so sorry for your loss and for the experience you had advocating. It is one thing to lose someone when you believe everyone did their best and that is came down to bad genetics or bad...
Thanks for posting. I'm very interested in the answers that will follow. Let me say that you are damn lucky to be receiving care in Germany!...
Thank you schoolpsych. What a great reflection. I'm curious about how your GP reacted when your PSA was so high and your cancer locally advanced. Do you get the sense that he/she will be offering...
That's wonderful news redwing. I hope your future results take on the shape of a concave down parabola! Celebrate!...
Thanks for sharing. It's a very valuable and important lesson and something that's easy to forget. I'm glad you and the good wife are ok. PS: You look very cute in a skirt...
Dear Mary, I'm so sad to read this news. My heart goes out to you. Dan was far too young. I"m glad he was able to enjoy his life until the end. Wishing you peace in the time to come. (((hugs))))...
If you are like us, you don't feel comfortable waiting for Abiraterone for CSPC to be approved for use and covered by insurance or medicare. We are trying to get funding but if we fail, my husband...
Naples, I liked this video from ASCO 2017 which is about the two studies (one was just for mets) related to Zytiga + ADT for hormone sensitive men. https://www.youtube.com/watch?v=9ICFqddSKYU Today...
Everton, I should have guessed Waterloo- the high tech capital of Canada, given that you are a computer guy. My daughters live in Waterloo (both engineers) and we are an hour away. We should get...
great tip! Thank you Cylone...
Everton, it must be a wonderful feeling to know that you are on the best treatment plan possible. You can't ask for more than that. I didn't know that you're Canadian. Are you receiving treatment in...
Does your hospital have a patient portal where you can access all reports and results? I find this to be very beneficial. Might be helpful in the future....
Glad you liked it Everton. I love very current audio/videos like this as you get the opinions of many Drs who are on the cutting edge of treatment....
Hello LOML, I'm sorry that this has happened but you've come to the right place. I'd ask to begin hormones ASAP- regardless of scans, it will stop/slow the progression of cancer. Wishing you the best....
Thanks for sharing your experience Pratoman. I found it very interesting. First, I want to say that you had a great surgeon if he did a frozen section. I begged and pleaded and the answer was "no". I...
I found this video to be very informative regarding the practice changes in response to the recent publications of the significant benefits of adding Zytiga to hormones for men on long term hormone...
Naples, the article in the New England Journal was published less than a month ago. Take a good look at the progression free survival of non-metastic men who had Xytiga + hormones vs those who only...
Tall Allen, Sorry to be so slow in responding to your post. The subject upset me so greatly that I didn't return to the thread. You wrote: You misunderstand the policy. The current task force...
Hello Naples! Your situations seems very similar to that of my husband. I found your stats here:http://www.healingwell.com/community/default.aspx?f=35&m=1217620&g=3875251#m3875251 It doesn't seem...
Thanks for the update. I wish your friend well. Please keep us posted....
Welcome Hotflash!Way to fight this battle! I'm glad you found us....
Mtnwife, I think all 4 pills are taken at once. If my husband can take 1/4 of the dose with breakfast (one pill) and we can find a source for generic Zytiga, the cost won't be so bad. As no bone or...
True, Fairwind. Another example is those who are hormone-sensitive and desperate to start Zytiga now in response to the NEJM publication. I might be wrong, but I think that Janssen might be providing...
Thank you Farz53 for getting back to me. Looks like India might be the country of choice. Thanks Cigafred for this reference. I wonder how BillyT is now? From reading his posts, I was able to trace...
Hello Susan, I was on holiday when you originally posted so I missed the opportunity to welcome a fellow Canadian wife. Like your husband, mine is not given to doing research and he relies on me....
The abstract of the study just says, "Low fat breakfast". http://ascopubs.org/doi/abs/10.1200/JCO.2017.35.6_suppl.176 The clinical trial information just says "conventional low fat breakfast"....
I wrote to one of the authors of the zytiga with breakfast study and asked him if taking 1/4 of the dosage would mean that the drug would work longer and he replied that he didn't think so. I asked...