WTH...our radiation experts can tell you about the differences between the newer scans that are available. Before you pull the trigger on treatment you will want to know where the enemy may reside....
First a Couple of questions : How old are you, what was your PSA, how many cores were positive and did the 3 T MRI show the cancer was outside the capsule. I was diagnosed as a G9 , PSA of 10 , age...
Mr. B. If possible, I would suggest you get a 3T MRI to more accurately stage your cancer and decide on treatment. The Partin Tables are statistical probabilities. The MRI is real time information....
Redwing...great news for a great contributor! Looking forward to more of the same....
Thianks for the perspective. We can never have too much perspective because without perspective our reaction to our cancer can delimit our lives long before our Cancer delimits our lives....
Redwing said : "I'll find some way to continue; I've always been willing to share my experiences. ". Please do. Your contributions are enormous! We all have a long journey ahead of us and we all need...
Redwing said: "I'm trying to limit and very narrowly focus my involvement now, and only reach out to try to provide support to G9-10 folks. Any research I'm doing from here, any opinions, I'll keep...
iSU Cyclone of course nails it when he says...."balance your life" . In order to balance your life you need to find an equilibrium. The equilibrium is the middle point between fighting your cancer...
While not directly on point to the discussion of the enhanced oncological control produced by a a double dip of radiation to the prostate gland , I think it is worth pointing out that a patient...
Halpert said: "EPE may or not mean anything". I am not challenging that statement because the whole discussion of PNI, EPE and Positive Margins is confusing to me. My naïveté I am sure stems from an...
A wonderful opportunity to try a new drug. Keep us informed as to how they introduce it ( fusion, injection) , dosage , frequency, and expectations and results....
Below is a quote from an article on the Prostate Cancer Foundation web site discussing the excitement around the Latitude Trial recomending moving Abirreterone to a first line treatment . It states a...
JNF said: "Also note that the newer classes of biologics like Keytruda (large molecule drugs usually ending in MAB) are considered Part D drugs under the 'Targeted Therapy" definition. Basically a...
The most understated aspect of Gleason 7, 8 and 9 is the risk of recurrence and progression .In the most favorable of circumstances, even where the cancer is capsule contained , the cancer can still...
Redwing...your response to Snowcake was well reasoned and excellent. Snowcake is understandably overwhelmed by the apparent rapidity of her Dad's cancer and has a right be angry that all of this is...
Tall Allen said: "If a patient wants to roll the dice that he is not among those who got a false negative mpMRI, that is certainly his call, but it's hard to see why he would accept such a risk...
Beth..it is extremely generous of you to offer the insight you will provide. All of the men momitoring/contributing to this site make decisions based on the eventual consequences of their choices....
Redwing..I share your excitement . And you have given men with a rising PSA a reason to hope when they are discouraged by a rising PSA. Now the hard job will be for someone to explain how, from a...
Allen's article on Lymph Node tracking and treatment cited above, is , as all things he writes , extremely well done. It is fair to say, however, that this is a PCA area , unlike others he addresses,...
Another view on the article: andrew goldstein| Health Business/AdministrationMar 23, 2017 As the article points out, this study contains many uncontrolled variables that make drawing conclusions,...
My Mayo choline scan for prostate cancer suprisingingly surfaced a 4. 3 cm thoracic aneurysm and a blockage in one of the ascending arteries. I contacted my cardiologist who said if it was 4.5 or...
Bohemond..it is fair to say that since you were first diagnosed in 2002 your prostate cancer has been well managed. You are now experiencing some faster PSA doubling times but the overall PSA is not...
TA said ": Lupron is more effective than Casodex alone, especially for someone who is castration resistant." TA .. I thought you would say Lupron was more effective than Casodex as a monotherapy, but...
TA said: " I don't know of any proven benefit of ADT3 over a single agent. The only important effect is that you take whatever is needed to prevent activation of the androgen receptor. Some MOs use...
Break60...the new met in the femur is a bummer after all you have done. You have chased your cancer wherever it went and did everything you could have done to cut it off at the pass. While we have...
These last few posts have dealt with the question of " what difference it all makes " once the cancer has left the gland, wherever it might have gone. The more one reads about prostate cancer the one...
Redwing...thanks for your answer. Would you think that if we looked at the same cohort at the 7, 10, and 15 year mark we would see an increasing narrowing of differences? The theory would be that the...
Tall Allen said: "ADT can extend your life. The trade off is a diminished QOL now with extended survival vs better QOL now with significantly shorter survival." Since I do not understand " Cox...
Redwing..at your age, or below age 65 ( an arbitrary to be sure cut off) I would recommend one do exactly what you are doing . Thus, the gravamen of my comments are addressed to the age 65 plus...
This is a great thread. I can't participate in the mathematical aspects of it, but it highlights the variability of prostate cancer not only in its original presentation but in its progressive...
Based on a PSA Doubling time of over two years, and assuming the best PET/CT scan is all clear, the decision to go on ADT now would, in my mind, be highly age dependent.Big difference between 55 and...
Allen...thanks for the great compilation of data. Assuming a patient selects a RO skilled at hypofractination, it seems like a no brainer. One thing that jumped out at me was the Hypro trial. It was...
142 . You have had Sugery, ADT , Radiation , Prolia, etc. It is not clear which of those you believe caused your bowel problems. If it was, you believe, radiation, that seems to be at odds with the...
"Ablation causes tissue changes that may change the prospects". The prevailing discussion of focal therapies is: " why not do it first? You can always remove the gland, deploy radiation, etc. The...
Merlin...I assume that neither of the two HiFU 's resulted in any ED or urinary problems so you are willing to do a third focal therapy thinking other options involve known side effects you wish to...
What is a Prostate Cancer Met? Good Question. I always understood that any cancer outside of the gland but in the bed, seminal vesicles, bladder neck was considered "locally advanced " prostate...
Thanks Tall Allen. There are so many takeaways from the article you cited I will not try to summarize them except to say that I conclude one needs to find the "Chris King's" wherever they might be...
I know that if one is interested in pursuing a Prostatectmy the advice is to find a high volume surgeon with a national reputation. With respect to SBRT there are numerous facilities now operating...
I am trying to understand what the prostate gland looks like Post Radiation and if the radiation did not kill the cancer how they find the cancer not killed. I understand the newer radiation...
Great Result!! Congratulations!!...
Thanks Again to All. I have been doing some more reading on High Risk disease and am beginning to understand its complexity. Redwing 57 . Thanks for the invite to the Club of 9's, not anything I...
Tall Allen. I thought " Dean Allen" and " your job " would be seen metaphorically not literally. But , as I said we have erased all of that. George has pointed out the G68 PSMA scanner I should look...
Tall Allen. Another great post until I got to the end: " I am sure you can find someone who won't challenge your misinformation or paradigm." Wow! The accolades you deserve for providing so much...
Thanks Guys for all of the advice to date . Tall Allen is our Dean for the obvious reasons: While he is always quick to caveat he is a non medic, I would put his knowledge, nuanced thought, insight,...
Halbert. No, I am a Yankee like so many on here. If you google Combidex you will get threads on its history. Short story :it is the best imaging agent ever invented. Has been extensively used in...
Age 73.PSA doubled 2. 4 to 5.6 in three years. 3 T MRI 12/15. Result : two suspicious lesions left lobe. Organ Confined. RADS 4. 3 D Mapped Biosy 5/ 16 : Gland size : 20cc. 41 Cores. 6 positive . One...
RecurrentPB......with the catheter still in I am sure nothing feels or looks positive. BUT you had as extensive of a biopsy as one can have and only 4 of 4 cores were cancerous and Gleason 6's at...
RecurrentPC Glad you are feeing better. Look forward to your future postings and updates. Could you tell us your core volume and Gleason Grade on the 4 cores. Tall Allen will Weigh in on: Was this...