Your treatment choice may vary depending on whether you prioritize survival or side effects. For young and healthy men with high-risk localized PCa they have better survival with RP compared with...
Antioxidants protect both healthy cells and cancer cells, if you have cancer they accelerate tumor development and cancer spread. It doesn't matter if the antioxidants comes from food or supplements....
Redwing - This study Surgery vs Radiotherapy in the Management of Biopsy Gleason Score 9-10 Prostate Cancer and the Risk of Mortality is not "lumped" with G8! Interestingly, the study concludes that...
I think oldbeek's URO is correct. The ultrasensitive PSA tests (anything below 0.1) often causes anxiety in the patients even when the reported PSA rise is clinically insignificant. So many who begin...
:blush: :confused: :cool: :cry: :devil: :eyes: :idea: :mad: :nono: :redface: :rolleyes: :( :scool: :shakehead: :shocked: :skull: :smhair: :) :-) :smilewinkgrin: :smurf: :tongue: :turn: :wink: :yeah:...
For those who lack Tall Allens view on current studies here is a link to his blog where he comments about whole pelvic radiation with short term ADT....
Smara - no, most recurrences happen between 2 - 5 years. Then the risk gets lower. If there were 100 men having surgery at the same time: 0 - 2 years: 18 men have BCR (82% recurrence free at 2 years)...
Yes, it will be harder for the body to handle attacks of cancerous cells if you have chronic anxiety. The anxiety can even open up new pathways through lymph system so that the cancer can spread more...
Will there be a way to "like" a post or a thread?...
I think this is an incorrect perception. One reason is that "the nadir+2 definition of failed RT" will delay the determination of biochemical failure for many years for those who chose radiation, as...
You mean Cyberknife? I guess nobody knows if it is feasible for ART/SRT yet. It could be! It has just not been tried out in enough number of trials. Efficiency and toxicity are not known. Here is one...
It is a huge difference if your PSA is .03 two months post surgery or two years post surgery. The former requires early SRT but for the latter it would be over treatment. There is absolutely no...
I was 100.0 % continent from day one. The one and only pad I ever tested was at catheter removal day and it was dry when I throw it away. Never experienced stress incontinence. The only difference...
I do as JNF and follow both forums. That forum seems to be somewhat smaller though, it currently has 4771 topics when this have 34086! Good that you have the same user name over there. I notice that...
At the same conference in Munich they also presented the RCT about Omega-3. Same result as for aspirin The largest and longest placebo-controlled randomized trial of omega-3 fatty acid (as found in...
"had to do Radiation..." Well, it's my impression lots of us surgery men have salvage radiation without really having to do it, at least not so fast. It's the ultra sensitive PSA tests that makes so...
Here is an "Han table" site where you can fill in your numbers and see a prediction of recurrence probability. Is this from where TA gets his numbers? It seems that TA used the preoperative tables...
There are several studies. One study from JAMA is worth mentioning: https://jamanetwork.com/journals/jamaophthalmology/fullarticle/1739520 (And yes, there are also several studies that have found no...
This is the first I've heard of the connection between statins and cataracts. I was started on atorvastatin/Lipitor at a pretty high dose (40mg) back in Sept. 2016 by my PCP. At a eye exam this past...
Both physicians and the public have been misled by the pharmaceutical industry. Public has got the feeling that statins prolong life for decades. According to the results of one of the first statin...
Its true that statins make people live longer. But how much longer? Have you ever asked your doctor? Do it at the next visit. Most people are surprised when they are informed that statins delay death...
Its might not be true that low carb is a healthier diet in the long term. The new study posted in The Lancet found that Low carb diet is associated with a lower expected life span with 15.000 people...
The other thread made me curious about mindfulness. I now think the reason why mindfulness works is you learn to control your breathing. It can actually be explained on a bio-chemical level how it...
I am glad that Zytiga is for free in Sweden (if I ever will need it). Sorry for those who needs it but can't afford it. Its not fair. Does anybody know in which other countries you get it without...
Yes, I remember that the two year PSA undetectable result was special. You can almost start believing it's all over with PCa at that time. Hope your result at the coming years will be the same. I...
Not sure JNF is correct. According to https://www.internationalinsurance.com/news/ranking-top-eleven-healthcare-systems-country.php US is ranked last of 11 Countries! In equity (what this thread is...
Is there any developed country on this planet except the United States where one's personal financial status limits one's medical treatment?...
Forgive me being skeptical to all this. Does the scientific research have any published results about mindfulness? Evidence that it is effective and better than other practices? Is there even a sharp...
If diet has an impact on PCa I would presume that soy will protect a man from PCa! In Asia they consume soy foods as part of a regular diet and they have lower PCa incidence than in Europe and US....
So one hypothese is that a life style that lowers your T would make the cancer grow slower? Unlikely, but if you want to lower your T level you should (and probably die of a hart attack): - high...
There is actually an ongoing clinical trial that will answer if SBRT is superior to surgery and conventional radiotherapy. https://clinicaltrials.gov/ct2/show/NCT01584258 There are several different...
An RO now? DonJ had ART Nov2014-Dec 2014 33 sessions 62GY. If the pelvic lymph nodes were not radiated then maybe they can be radiated now, or?...
My understanding is that Gleason grade is established early in tumor pathogenesis and typically does not progress (but it happens). That is why men with lower grade disease can feel relative...
From Worldwide status of vitamin D nutrition it seems that the difference is more complicated than northern and southern climate. Vitamin D deficiency (serum 25(OH)D<25 nmol/l) is highly prevalent in...
Some say there is a U-shaped association, with elevated disease risks at both high and low D! It is not surprising that few men on HW was "sufficient". It has been estimated that over one billion...
richh - an observational study of vitamin D and greater risk for a disease can suggest only a correlation, not a cause-and-effect between the two things. Only an RCT can do that. The RCT that Tall...
I don't think Epstein was wrong. The prostate specimen is step-sectioned at 4-mm intervals of the gland. A small amount of pattern 5 could be contained within one of the 4 mm slices, unseen by the...
The actual quantity of pattern 5 originally detected in the biopsy core turned out to be so small that it could not be found by the pathologist who examines the surgically removed prostate (but...
Don't agree on InTheShop approach. What if the low D is a consequence (or a marker) of a disease, or aging, or obesity, or smoking, or inactivity, etc. Supplementing will not fix any of those. Must...
Allen, why aren't these scans also used during primary staging and therapy planning? Are they only valuable after BCR? Can't they add/complement information to mpMRI?...
Common supplements seem to have potential to shorten your life, at least in older women but why would older men be different? "The Iowa Women's Health Study"...
You can hardly get more evidence than a level 1 study. Also this quote looks like a good argument for giving up on D for men with PCa. Vitamin D is a potent hormone (like testosterone) and we maybe...
Has there really been any official recommendation in the United States that suggests vitamin D for anyone other than risk groups, i.e.: children under 2 years old, pregnant women, older people who...
Our brain cells need glucose to work. Glucose comes from breaking down carbohydrates and therefore low and zero-carb diets have a strong potential for negative impact on learning, thinking and...
Despite the better outcomes for EBRT+BT there is a shift towards surgery and away fot BBT for high risk cases in US. I found these numbers (don't know how accurate they are). Between 2000 - 2005, 24%...
Another possible explanation is that the development of cataracts is influenced by his ADT treatment. SEs from ADT like weight gain, insulin resistance, dyslipidemia, are known risk factors for...
PSA assays from different vendors (as all immunoassays) do not correlate well as this link demonstrates. Immunoassays are notorious for their lack of acceptable correlation across vendors. During the...
RT w/o ADT was comparable with RP. If ADT is responsible for the improved RT outcomes why isn't ADT also an option to use together with RP for high-risk cases? But then falls one argument for RP,...
Interesting, is this challenging the the TOAD study in some way? That trial concluded "Immediate receipt of androgen-deprivation therapy significantly improved overall survival compared with delayed...
This nomogram which predicts whether a recurrence after radical prostatectomy can be treated successfully with SRT could be interesting for you....