hey just touching base as my uPSA is now 0.026 as of 6/10/22 and rising 6 years after RP. Just got a new uPSA blood test today and SRT looks probable. Was wondering if you have any more advice on SRT...
Mack is smart nice guy, had a quick chat with him...
thx for information...
hey thanks for the information...
my uPSA has been rising slowly to now 0.018 from 0.008 in the last 18 months, 5 years post 3+4 RP at UCSF I might need SRT and ADT sometime next year at age 61 I need to do healthcare insurance...
this figure summarizes this https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527538/figure/F1/ from the uPSA 0.03 BCR Kang study https://www.ncbi.nlm.nih.gov/pubmed/25463990 PURPOSE: Integrating...
I just found the picture with the study which seems to state that the odds are 50 - 50...
franpro let me know how and when you proceed, best wishes...
halbert enjoy the < 0.06 7 years post RP I have climbed from < 0.06 to 0.012 in around 2 years it was a bit realistic and frightening that you stated that 0.02 is a major threshold which I agree with...
DjinTonic yes your uPSA readings might be slightly worse than mine as they are 0.015 vs 0.012 the good news is that you have been flat for 10 months what concerns me is that BCR is now effectively...
your signature has just one less than < sign does 1-14-19 0.01 mean 0.01 or < 0.01 ? the 1-6-14 0.06 seems high but dropped ? Post-Op PSA's 5-23-13 <0.10 1-6-14 0.06 1-21-15 0.01 1-11-16 0.01 1-12-17...
DjinTonic I wonder if my good gnmemoic health decipher score 0.22 also reduces my BCR risk or just my metastatic risk?...
a study to look at with respect to uPSA, BCR and SRT Very early salvage radiation has up to fourfold better outcomes and saves lives...
alephnull I appreciate your take, the odds are in my favor but they are not 100%...
OldTiredSailor thx will look at the study the key with SRT is if and when to pull the trigger how did they define BCR and when to pull the trigger in this study? this older study from late 2016...
BillyBob@388 pasayten is doing great despite having had BCR and SRT unlucky with Gleason 3+3 pasayten signature 3/2007 - Dx 59 y/o 12 pt biop - L 0/6 R 1/6 - G 3+3 T1c 4/2007 - DaVinci - G6 T2c Nx Mx...
fiddlecanoe thx for the details the doctors are still sort of confused on when and how to act some guys who I feel sorry for are still in the dark ages not using uPSA you were in the unlucky 13%...
pasayten thx for the perspective glad that your uPSA has plateaued for a bit btw nice work getting tested uPSA monthly on the extended signature...
the landscape is different for someone in great health at age 60 compared to some guys at age 76 even more diffecnt for guys that get prostate cancer at 80+ everyone is different but hopefully,...
halbert for myself quantifying risk and hearing about the journeys of others in a similar situation is very helpful for me statistics are useful in terms of being concerned or being relaxed many guys...
InTheShop (Andrew?) I did find this figure https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527538/figure/F1/ from the uPSA 0.03 BCR Kang study Is the risk of BCR 50% for post RP guys with a uPSA of...
fiddlecanoe thx curious as to your uPSA history if you have dates and numbers these days the new breakpoint is once your uPSA crosses 0.03 getting BCR and SRT is just a matter of when not if I am not...
thx BillyBob@388 for your response the Prostate Cancer Nomograms gives me 89% of being BCR free which does not account for post RP uPSA levels Prostate Cancer Nomograms also use 0.2 for BCR despite...
thx Pratoman, you are partially right I like to be in touch with guys that are on the same path with me I have two friends both cyclists locally out here that were 2 years post RP with me and we all...
thx DjinTonic curious as to your exact full uPSA history as my Decipher score is 0.22 also low risk you were 0.01 post RP which is not great but your doubling time is great 0.010 to 0.015 in over 2...
Octorobo, thx I am essentially ahead of you being 0.012 at year 4 just collecting stories and outcomes great news on the blind early SRT, it works for some and not for others good luck on your next...
does this apply to low and intermediate-risk post-RP guys? https://www.ncbi.nlm.nih.gov/pubmed/25463990 "PURPOSE: Integrating ultrasensitive prostate specific antigen with surveillance in patients at...
hey halbert, thanks for the input I do take supplements such as Tumeric that mask PSA but stop taking them 72 hours before my uPSA test. I think most of these supplements flush out of the body in a...
hey DjinTonic, thanks for the input I do take supplements such as Tumeric that mask PSA but stop taking them 72 hours before my uPSA test. I think most of these supplements flush out of the body in a...
Dr. Epstein is a must in my opinion. Low cost, quick and done by practically everyone. A genetic test is also good. I did the Oncotype DX Genomic Prostate Score Test...
Lower PSA levels are only desirable if the lower PSA levels are caused by lower cancerous activity. https://pcnrv.blogspot.com/2019/04/if-you-are-using-psa-to-monitor-your.html If you are using PSA...
I was hoping to hear of anyone or anyone that knows anyone that has avoided BCR. It seems odd that no one seems to know of such a guy....
thx InTheShop do you know of anyone or anyone that knows anyone that has had longterm stable uPSA values? my odds of BCR seem to be 100% as I can find no one on any forum including this one that has...
I am just ideally looking for some clinical data. Opinions, 1st hand accounts and 2nd hand references are fine too....
djin halbert thanks for engaging I wish I was still at < 0.006 as that ended 18 months post RP been going downhill for the last 30 months with a steadily rising uPSA to 0.012 my background is...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106725/ "In the multivariate analysis, statistically significant differences were observed only in pathological nodel stage within the PSA nadir <0.008...
Robert / Bobbiesan I would like to keep in touch if that is possible. the low uPSA is a shared experience. I hope my outcome is good too as yours currently is. I like your thoughts and approach like...
RobLee nice thinking always recheck assumptions assume = make an ass out of u and me got that drilled into my head at 14 by my AP Chemistry teacher, served me well in life including as pretty easy...
Bobbiesan, btw I cycle for exercise by and large which might raise your testosterone and muscle mass along with boosting your immune system and general health. I suggested to the guy needing TRT to...
Bobbiesan, could explain this as I am a newbie and pretty ignorant of hormones (along with many other areas despite being a CalTech grad, humulity is a good thing btw) Was Androgel used to correct...
best wishes, your advice is great about each day being the daily gift is an absolute truth, guys like you are my heroes...
curious to your uPSA history before 2/17 0.024 all < 0.015 correct ? 2/17 was 58 months (~5 years) post RP? how maniy months TRT occurred before 2/17 0.024 ?...
tony w - hey congrats zero is better than anything but low and stable after 10 years is a VERY close second after 10 years your odds keep on getting better, much much better I would be very curious...
kwoo64, thx Close margins are riskier but typically functionally negative as cutting tissue destroys cells on both sides. 7 years is a long time, I have measurable uPSA at 4 years (0.011) Looks like...
kwoo64, thx looks like uPSA typos you got your first non zero uPSA post RP at July 2018 0.04 OR July 2017 0.07? The doubling time is key as doubling times less than a year can be cancer your dates...
Pratoman, thx my pre RP PSA was 5.0 (free PSA 8%, would be nice if the Nomogram used this) my margins were negative but exceedingly tight less than 0.1 mm from ink (Epstein reconfirmed) plugged in...
pasayten thx for your input hopefully your G6 is not too aggressive...
oldbeek, thx watched the video. the complaint was about the standard PSA test being used at it's error prone lower limits. the uPSA test is theoretically better as my readings are above the lower...
oldbeek, thanks curious to what your entire PSA history is from post RP also your gleason score and pre RP PSA in particular the timing of the ups and downs I use the uPSA test so I have 3 decimal...