It's quite common that by the time a man is diagnosed with PCa, there are already multiple lesions, and it's common that they have different Gleason scores (which is basically their severity). (1)...
That reminds me of another. A boy in a Catholic school is trying to avoid discipline by hiding behind a confessional. He overhears another boy confessing to the priest that he's kissed three girls....
Hi Jason. Remember, we are not doctors. That said, I am baffled by the AS recommendations given your very strong family history and biopsy findings. The strongest weapon in the arsenal is early...
My condolences to you and your family, Skeeter. Djin...
Timing of radiotherapy (RT) after radical prostatectomy (RP): long-term outcomes in the RADICALS-RT trial (NCT00541047) (2024, Full Text) " Highlights • 1396 participants were randomised (2007 to...
The best (strictest) AS programs have a PSA of <10 as an entry requirement and bump people off--recommending treatment--for those in their program whose PSA climbs over 10. I think most wouldn't...
I'd just add that in weighing the pros & cons of RP vs RT for treating localized PC, his age is not a factor against surgery. See also Localized prostate cancer in older patients: Radical...
Why Do Only Dogs and Humans (and Maybe Lions) Get Prostate Cancer? Similarities of prostate and breast cancer: Evolution, diet, and estrogens (2001) Donald Coffee "Abstract Environment determines...
Our PCP, an internist, is retiring in a few months, and, when asked, suggested two of his several practice partners (all internists), who were accepting patients. By coincidence, one of the two...
The dorsal venous complex (DVC) consists of of small veins that drain the pelvis and run together on top (along the base) of the prostate. I'm not sure why it lit up. You should bring this up for...
See also Does The Old Farmer's Almanac Really Help When It Comes To Planting Vegetables? ...
I agree with your interpretation, Jota. SRT for a BCR of 0.2 to 0.5 is still considered "early" and administering "very early" SRT at 0.1 is more often advised for post-RP men considered to be at...
This is encouraging, Larry....
If for whatever reason insurance declines the PSMA-PET scan, I would appeal the decision with the backing of one of his doc. ----------------------------------- Yes, but brachy as a RT boost--AFAIK,...
One of my favorite musicals is Ant Misbehavin'....
P.S. **IF** further imaging does not reveal any positive regional lymph nodes or more distant metastases, you may want to discuss with your docs the benefits of having a Decipher test done. This test...
Men who have a high-grade or very high-risk diagnosis should be told upfront that surgery monotherapy is not standard of care if their cancer is not prostate-confined. In my case, I was spared both...
One study that I saw found that it's often the case that all the mets one develops derive from a single lesion in the prostate. PCa is called a heterogeneous disease: it's not unusual that a man at...
As your report points out, at PSAs around 0.5, the chances of finding existing lesions have just crossed over the 50% line. One approach would be to presume that recurrence is present and it's more...
I would think his uro already knows the size (and shape) of his prostate and his PSAD (PSA density). My understanding is that TRUS equipment--also used for TRUS biopsies--automatically calculates...
Ben comes in late to Friday night service at an orthodox synagogue. As he's walking down the aisle he sees, seated alongside his friend Abe, a dog wearing a tiny yarmulke and tallit, with a prayer...
Everyone is happy for you! Djin...
Hi Sela, and Welcome to you! Don't be surprised or unduly concerned if the MRI is negative and his uro still wants a biopsy, given that it would be (I assume) his first. As has been mentioned,...
The analysis was done by a Monte Carlo simulation program (MISCAN) that's been around for some time and still in use. The R statistical programming language was used for the curve-fitting. The...
Exploring the relation of active surveillance schedules and prostate cancer mortality (2024, Full Text) " Abstract Background Active surveillance (AS), where treatment is deferred until cancer...
Tissue-Based Genomic Testing in Prostate Cancer: 10-Year Analysis of National Trends on the Use of Prolaris, Decipher, ProMark, and Oncotype DX (2024, Full Text) " Abstract Background: Prostate...
"Being a pT3a is also a concern." Yes. Was there advice to plan SRT when your PSA began to rise above 0.2 given your were upgrade to G(4+3) and extraprostatic extension was found at your surgery?...
It would have been helpful if you mentioned in your first post that you switched test methods for your last PSA test (you later mentioned Quest). It makes last year's 0.03 and this year's 0.06 harder...
It's curious how some hospitals and doctors' offices (rightly) make a big deal over HIPAA practices and consent forms, yet have no qualms about calling your full name out loud in the waiting...
Sorry if I was unclear. I changed "If it's slowly rising" to "If mine is slowly rising" to make it clear I was talking about my own PSA in that sentence :) Your values could certainly be...
I would say it depends on two factors. First, your comfort level. You might have more peace of mind with the standard test. Or you could have it with the 3-decimal Labcorp test, where most of the...
Hi Beachbum. You've gained knowledge. A result of <0.01 means that your PSA could be anything below that--even as high as 0.099. Your latest result means your PSA might even be more than 10 times...
From the NIH's PDQ, linked above: "The only fully reported clinical trial of the use of pomegranate juice in men with prostate cancer showed that, on average, study participants who drank the juice...
Yes, always read the labels. Some "pomegranate juices" aren't all pomegranate, but are mixtures with apple, grape, or other juices. IMO a better bet are capsules of extract made from the whole...
I'm sorry to hear this but wish you both much better news going forward in the fight! If you husband hasn't already had germline testing, I would ask about it (although I'm sure the specialists will...
PDQ Guides are published by the NIH--National Cancer Institute and are available on a variety of topics, including prostate-cancer diagnosis and treatment. They are all regularly updated and a very...
I believe that any reduction in PSA from supplements is not very large. In any case, if you develop PCa, your PSA will rise--supplements will not keep it down. However, it's a good idea to let your...
i took Pomi-T for a few years, but found it was cheaper to buy the four individual ingredients separately, especially if you want larger doses. Tumeric curcumin can lower the PSA a bit. There is no...
Keep in mind that with Labcorp's uPSA test, if you repeat the test many times on the same blood draw , you will get results that fall within ±0.002 of your actual value in ideal test condition, and...
The press release? It clearly has one foot in marketing--that's one meaning of "press." The other article points to Decipher results influencing SOC: "In patients with NCCN high-risk and a Decipher...
You may want to discuss with your docs the value of (1) genomics testing of your biopsy tissue (looking at your tumor's RNA and its propensity to metastasize--e.g. the Decipher Biopsy test) as others...
Decipher prostate test receives high evidence rating in NCCN guidelines (2024) Urology Times article "The Decipher Prostate Genomic Classifier has received a Level 1B evidence rating, the highest...
Hi Mumbo. I briefly discussed the PSMA insurance question about with my uro last visit and he thinks that, as with any new technology, it's going to take a little time for things to be worked out...
The Current Landscape of Prostate-Specific Membrane Antigen (PSMA) Imaging Biomarkers for Aggressive Prostate Cancer (2024, Review, Full Text) " Simple Summary The review explores the critical role...
That is excellent! Djin...
Hi M1961, Thank you for the post and link the the paper. The paper's proposal for PSMA + MRI at 0.3–0.5 ng/ml or above is too late for G9 men according to D'Amico. As I see it, if I have imaging done...
That's good x 2. Stay positive! :)...
Thanks! According to the company, a Decipher RP score correlates with the Decipher Biopsy score about 70% of the time (I think this is stated in tiny print at the bottom of your Decipher report.) As...
The upcoming PSA test is important, because if you have "persistent PSA" (0.1 or higher) and it's confirmed, adjuvant therapy will most likely be recommended after a healing period. I suggest asking...
Hi Jack. Thank you for the kind words, but believe me when I say I'm not especially frustrated--rather I'm twiddling my thumbs publicly. My uro just responded to my message and latest uPSA showing...